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Drug Interaction Checker

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33 Drug Interactions Found
Severe severe interaction
mmr vaccine+cortisone
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Inform your health care provider you are taking a Corticosteroid before receiving any Vaccine. In some cases, Vaccines should not be given to persons taking a Corticosteroid for the treatment of a chronic inflammatory health condition like asthma or arthritis. Treatment with Vaccines may result in infection or other side effects in patients receiving Corticosteroids, especially long-term or high dose therapy. Discuss Vaccination options with your health care provider. Also, avoid contact with anyone who has recently received the oral poliovirus vaccine. Topical Corticosteroid products should not interact with Vaccines.
Severe severe interaction
mmr vaccine+certolizumab
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Inform your health care provider you are taking Certolizumab pegol before you receive any Vaccine. Certolizumab may decrease the actions of Vaccines. If you are taking Certolizumab, you should not receive certain types of vaccines known as "live virus vaccines" (examples: Biavax II, Orimune, Varivax). Discuss Vaccination options with your health care provider. Also, avoid contact with anyone who has recently received the oral poliovirus vaccine. If you experience fever, chills, or other symptoms of illness, contact your prescriber immediately.
Severe severe interaction
mmr vaccine+mercaptopurine
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Inform your health care provider you are receiving Chemotherapy before receiving any Vaccine. Certain Live Vaccines may not be appropriate for patients taking Antineoplastic Agents (chemotherapy, medicine used to treat cancer and other conditions). Treatment with some vaccines may result in infection in patients receiving Chemotherapy. Discuss Vaccination options with your health care provider.
Severe severe interaction
mmr vaccine+mitoxantrone
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Inform your health care provider you are receiving Chemotherapy before receiving any Vaccine. Certain Live Vaccines may not be appropriate for patients taking Antineoplastic Agents (chemotherapy, medicine used to treat cancer and other conditions). Treatment with some vaccines may result in infection in patients receiving Chemotherapy. Discuss Vaccination options with your health care provider.
Severe severe interaction
mmr vaccine+dactinomycin
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Inform your health care provider you are receiving Chemotherapy before receiving any Vaccine. Certain Live Vaccines may not be appropriate for patients taking Antineoplastic Agents (chemotherapy, medicine used to treat cancer and other conditions). Treatment with some vaccines may result in infection in patients receiving Chemotherapy. Discuss Vaccination options with your health care provider.
Severe severe interaction
amprenavir+Alcohol
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Amprenavir Oral Solution contains a large amount of an alcohol-like solution. Avoid Alcohol-containing products or beverages while taking Amprenavir Oral Solution, as excessive sedation (difficulty staying alert), dizziness, or difficulty breathing may occur. Alcohol does not appear to interact significantly with Amprenavir capsules.
Severe severe interaction
posaconazole+ranolazine
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Do not take Ranolazine and Posaconazole together without first getting approval from your prescriber. The risk of serious side effects from Ranolazine may increase if you take Posaconazole. A change in the dose of Ranolazine may be necessary. Contact your prescriber if you experience chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your heart beat (such as a fast or irregular heart beat) while taking Ranolazine.
Severe severe interaction
lidocaine+ranolazine
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Although these drugs can interact, Lidocaine is usually used in a hospital or clinic during surgery or a procedure to reduce feelings of pain (numb) in the area being treated during the procedure. Side effects from Lidocaine may get worse if you take Ranolazine. In theory, Ranolazine can lead to decreased elimination of Lidocaine from the body. Although an interaction is possible, these drugs may be used together. Taking these drugs together can increase the risk of a dangerous change in heartbeat or heart rhythm. Promptly report to your health care provider side effects such as severe drowsiness, tremor, chest pain or irregular heartbeats, or confusion. The topical forms of Lidocaine that you apply to your skin probably will not interact with Ranolazine.
Severe severe interaction
droperidol+butorphanol
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The dose of Mixed opiate agonists/antagonists may need to be lowered when Droperidol is also used. Discuss your drug regimen with your health care provider prior to any surgeries or procedures. You may also feel drowsy or more tired when taking these drugs together. Do not stand or sit up too quickly as you may become dizzy or feel faint. Do not drive or operate machinery until you know how these drugs affect you. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, tell your health care provider immediately.
Severe severe interaction
droperidol+ranolazine
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Do not take Ranolazine with Droperidol. Although very rare, taking these drugs together may increase the risk of a dangerous change in heartbeat or heart rhythm. Contact your prescriber immediately if you experience chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your usual heart beat (fast, slow, or irregular heart beat) while taking these drugs together.
Severe severe interaction
droperidol+Alcohol
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Avoid alcohol-containing drinks while taking medicines that cause drowsiness like prescription pain medicines, medications to reduce anxiety, medicines to induce sleep or sedation, and medicines used for colds or allergies. Using some of these drugs along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Severe severe interaction
butorphanol+Alcohol
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Avoid alcohol-containing drinks while taking medicines that cause drowsiness like prescription pain medicines, medications to reduce anxiety, medicines to induce sleep or sedation, and medicines used for colds or allergies. Using some of these drugs along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Severe severe interaction
ranolazine+Grapefruit juice
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Avoid taking Ranolazine with grapefruit juice. Grapefruit juice and grapefruit-containing foods may increase the risk of serious side effects from Ranolazine. A change in the dose of Ranolazine may be necessary if Ranolazine and grapefuit juice are used together. Contact your prescriber immediately if you experience chest pain, dizziness, fainting or falling spells, palpitations, or changes in your usual heart rate (fast, slow, or irregular heart beats) while taking Ranolazine.
Moderate moderate interaction
cortisone+droperidol
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Corticosteroids may decrease the level of potassium in your blood. Normal potassium levels are important during therapy with Droperidol. When the potassium in the blood is too low, this can cause muscle cramps, weakness, or an abnormal heart rhythm. Your health care provider can monitor your potassium level. A potassium supplement may be prescribed for patients with a low potassium level. Contact your prescriber immediately if you experience chest pain, dizziness, fainting or falling spells, palpitations, or change in your usual heart beat (fast, slow, or irregular heart beat) during therapy with Droperidol.
Moderate moderate interaction
cortisone+metaproterenol
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Side effects from Pirbuterol may get worse if you take Corticosteroids. Although an interaction is possible, these drugs are often used together. Your health care provider may need to monitor your potassium levels with a blood test. Discuss any new or worsening side effects with your health care provider.
Moderate moderate interaction
nevirapine+lidocaine
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Nevirapine may decrease the actions of Lidocaine injections. Your prescriber may need to do blood tests or check your heart rhythm (using an EKG) to make sure you are receiving the correct amount of Lidocaine. Contact your prescriber immediately if may experience chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your usual heart beat (fast, slow, or irregular heart beat). Nevirapine should not interact with skin or topical products containing Lidocaine.
Moderate moderate interaction
nevirapine+ranolazine
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Do not take Nevirapine and Ranolazine together without talking to your health care provider. Nevirapine can decrease the actions of Ranolazine. Contact your physician promptly if you experience an increase in the number or severity of angina attacks while taking Nevirapine. Symptoms of an angina attack might include chest pain, reduced tolerance of exercise or walking, and/or shortness of breath.
Moderate moderate interaction
amprenavir+lidocaine
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Lidocaine injection is only used in a hospital or clinic during surgery or procedures to reduce feelings of pain (numb) the area being treated or to treat serious irregular heart rhythms. If you are taking Anti-Retroviral Protease Inhibitors (medicines to treat HIV infection and AIDS) and receive Lidocaine, you may be at increased risk of developing a change in heartbeat (palpitations) or very low blood pressure during the procedure. Talk to your health care provider before any surgeries or procedures and inform them that you have been taking Protease Inhibitors. Protease Inhibitors should not interact with skin or topical products containing Lidocaine.
Moderate moderate interaction
ceftriaxone+tobramycin
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Cephalosporins have caused kidney problems when mixed with aminoglycosides (Garamycin, Nebcin) which are known to cause kidney problems in some people.
Moderate moderate interaction
ceftriaxone+calcium citrate
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Although an interaction is possible, Ceftriaxone (Rocephin) is usually given in a hospital or clinic setting. Ceftriaxone and Calcium Salts given through a vein (IV or intravenous) should not be given together or within 48 hours of each other. When given together, small particles may form in the body and cause problems in the lung or kidney, especially in newborns. If these drugs are prescribed to you, your healthcare provider will closely monitor your condition. Let your healthcare provider know if you are taking large amounts of calcium supplements.
Moderate moderate interaction
tolcapone+droperidol
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Although Droperidol and COMT inhibitors like Entacapone and Tolcapone can interact to increase drowsiness, generally, Droperidol is only used in a hospital or clinic. Discuss your drug regimen with your health care provider prior to any surgeries or procedures. Do not stand or sit up too quickly as you may become dizzy or feel faint. Do not drive or operate machinery until you know how these drugs affect you. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, tell your health care provider immediately.
Moderate moderate interaction
tolcapone+butorphanol
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You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how these drugs affect you. Discuss any new or worsening side effects, like confusion, with your health care provider.
Moderate moderate interaction
tolcapone+Alcohol
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Avoid alcohol-containing drinks while taking Tolcapone. You may feel drowsy or more tired when taking these drugs together, and alcohol can interfere with the effectiveness of Tolcapone treatment by affecting your balance and movements. Do not drive or operate machinery if you are drinking alcohol-containing beverages.
Moderate moderate interaction
droperidol+metaproterenol
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Droperidol is generally only used in a hospital or clinic, for surgical- or procedure-related nausea and vomiting. Discuss your drug regimen with your health care provider prior to any surgeries or procedures. Very rarely, Beta-agonists (commonly used as respiratory treatments) have also caused changes in heart rate or rhythm. Examples of Beta-agonists include: Advair, Combivent, Foradil, Proventil, Serevent, and Ventolin. Additional risk factors for this rare interaction include females, patients with certain pre-existing heart conditions (such as prior heart attack, angina, heart failure, heart rhythm disturbances), patients receiving certain Diuretics (water pills such as Hydrochlorothiazide) which can decrease the level of potassium in the blood, patients with a low potassium level in the blood due to excessive vomiting or diarrhea, or patients with congenital Long QT syndrome (a rare genetic syndrome). Seek medical attention immediately if you notice side effects like chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your heart beat (such as a fast or irregular heart beat) while taking these drugs together.
Moderate moderate interaction
ranolazine+metaproterenol
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Ranolazine and Beta-agonists may be prescribed together under the supervision of your health care provider. Examples of Beta-agonists include: Advair, Combivent, Foradil, Proventil, Serevent, and Ventolin. Ranolazine can increase the risk of a dangerous change in heartbeat or heart rhythm. Very rarely, Beta-agonists have also caused changes in heart rate or rhythm. Additional risk factors for this rare interaction include females, patients with certain pre-existing heart conditions (such as prior heart attack, angina, heart failure, heart rhythm disturbances), patients receiving certain Diuretics (water pills such as Hydrochlorothiazide) which can decrease the level of potassium in the blood, patients with a low potassium level in the blood due to excessive vomiting or diarrhea, or patients with congenital Long QT syndrome (a rare genetic syndrome). Seek medical attention immediately if you notice side effects like chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your heart beat (such as a fast or irregular heart beat) while taking these drugs together.
Moderate moderate interaction
metaproterenol+Caffeine-containing Foods/Beverages
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Limit excessive Caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Sympathomimetics and avoid medicines containing additional Caffeine whenever possible. Examples of Sympathomimetics include medicines used to treat asthma and other breathing problems like Albuterol, Arformoterol, Formoterol, Salmterol and others. Taking a high amount of Caffeine with the listed drugs can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, or other side effects.
Minor minor interaction
cortisone+mercaptopurine
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Although an interaction is possible, these drugs are often used together. Additive benefits may occur when Corticosteroids (examples: Dexamethasone, Methylprednisolone, Prednisone, or Prednisolone) and Antineoplastic Agents (chemotherapy, medicine used to treat cancer and other conditions) are used together. The combined therapies are often designed to take advantage of these benefits. However, some side effects may include an increased risk of infection. If you notice signs or symptoms of an infection, such as a fever, sore throat, etc., do not treat yourself and seek your prescriber's evaluation and advice.
Minor minor interaction
cortisone+mitoxantrone
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Although an interaction is possible, these drugs are often used together. Additive benefits may occur when Corticosteroids (examples: Dexamethasone, Methylprednisolone, Prednisone, or Prednisolone) and Antineoplastic Agents (chemotherapy, medicine used to treat cancer and other conditions) are used together. The combined therapies are often designed to take advantage of these benefits. However, some side effects may include an increased risk of infection. If you notice signs or symptoms of an infection, such as a fever, sore throat, etc., do not treat yourself and seek your prescriber's evaluation and advice.
Minor minor interaction
cortisone+dactinomycin
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Although an interaction is possible, these drugs are often used together. Additive benefits may occur when Corticosteroids (examples: Dexamethasone, Methylprednisolone, Prednisone, or Prednisolone) and Antineoplastic Agents (chemotherapy, medicine used to treat cancer and other conditions) are used together. The combined therapies are often designed to take advantage of these benefits. However, some side effects may include an increased risk of infection. If you notice signs or symptoms of an infection, such as a fever, sore throat, etc., do not treat yourself and seek your prescriber's evaluation and advice.
Minor minor interaction
nevirapine+amprenavir
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Although an interaction is possible, these drugs are sometimes used together. Nevirapine may decrease the blood levels of Amprenavir. If your prescriber decides that taking these drugs together is best for you, an increased dose of Amprenavir may be prescribed while you are taking Nevirapine.
Minor minor interaction
amprenavir+Grapefruit juice
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Although an interaction is possible, it is usually okay to drink grapefruit juice or eat grapefruits while taking Amprenavir. In theory, side effects from Amprenavir such as diarrhea, headache, or rash might get worse if you drink grapefruit juice or eat grapefruits, but significant interactions have not been reported. Do not greatly alter your normal grapefruit and grapefruit juice intake while taking Amprenavir.
Minor minor interaction
amprenavir+High Fat Foods
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In general, it is okay to take Amprenavir with or without most foods. However, very fatty meals can decrease the absorption of Amprenavir into the body and it is recommended that you avoid taking Amprenavir with a high-fat meal. Although an interaction is possible, it is also usually okay to drink grapefruit juice or eat grapefruits while taking Amprenavir. In theory, side effects from Amprenavir such as diarrhea, headache, or rash might get worse if you drink grapefruit juice or eat grapefruits, but significant interactions have not been reported. Do not greatly alter your normal grapefruit and grapefruit juice intake while taking Amprenavir.
Minor minor interaction
paroxetine+Alcohol
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In general, it is recommended that you avoid Alcoholic drinks while you are taking Paroxetine (Paxil). Alcohol can affect the mood and interfere with the drug treatment, and may increase the risk of side effects. Do not drive or operate machinery if you are drinking alcohol-containing beverages.
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This feature is for informational purposes only and should not be used to replace the care and information received from your healthcare provider. Please consult a healthcare professional with any health concerns you may have.

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