Drug Interaction Checker

You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how these drugs affect you.

Barbiturates are commonly used for sedation, seizures or for sleep and include drugs like Amytal, Buticaps, Mysoline, Nembutal, Phenobarbital, and Seconal. Caffeine may cause sleeplessness, so if you are taking a barbiturate to help you sleep, you may wish to avoid taking caffeine and caffeine-containing foods like colas, coffee, teas, or chocolates within several hours prior to bedtime. Barbiturates may also decrease the actions of Caffeine; if you have a high intake of caffeinated foods or beverages you may experience a headache or irritability from decreased caffeine levels while taking these drugs until your body adjusts. If you take Caffeine for other purposes, notify your health care provider if you think Caffeine is not working as well for you.