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Drug Interaction Checker

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23 Drug Interactions Found
Severe severe interaction
albuterol+epinephrine
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While you take Albuterol, use Sympathomimetic drugs with caution because additive side effects may occur. Examples of Sympathomimetics include stimulants like Amphetamine, Adderall, Dexedrine, Ephedrine, Fastin, and Tenuate; some cough and cold products containing Pseudoephedrine (example Sudafed), Phenylephrine, or Phenylpropanolamine (PPA); and also herbal weight loss products containing ephedra or Ma huang. Taking the listed drugs with Albuterol can increase the risk of a fast heart rate, nervousness, palpitations, problems with sleep, or other side effects.
Severe severe interaction
propoxyphene+Alcohol
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Avoid alcohol-containing drinks while taking medicines that cause drowsiness like prescription pain medicines, medications to reduce anxiety, medicines to induce sleep or sedation, and medicines used for colds or allergies. Using some of these drugs along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Severe severe interaction
clemastine+Alcohol
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Avoid alcohol-containing drinks while taking medicines that cause drowsiness like prescription pain medicines, medications to reduce anxiety, medicines to induce sleep or sedation, and medicines used for colds or allergies. Using some of these drugs along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Severe severe interaction
epinephrine+ergotamine
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Although Epinephrine and Ergot Alkaloids can interact, generally, Epinephrine is only used in for emergency purposes, such as self-treatment of a life-threatening allergic reaction, or in a hospital or clinic. In general, do not take Epinephrine and Ergot Alkaloids (examples include Cafergot, Ergotrate, Ergostat, Hydergine, Methergine, Migranal, Sansert or Wigraine) together in other situations. Taking Epinephrine with Ergot alkaloids can increase the risk of chest pain, high blood pressure, palpitations, or other serious side effects.
Severe severe interaction
ramelteon+Grapefruit juice
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Do not take Ramelteon with grapefruit or grapefruit juice. Taking Ramelteon with grapefruit or grapefruit juice can increase the amount of Ramelteon in the blood and can increase the risk of serious side effects. Swallow Ramelteon with some water within 30 minutes before you are ready to go to bed. Tell your health care professional if your sleep problem does not improve or gets worse.
Severe severe interaction
ramelteon+Alcohol
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Avoid alcoholic drinks while you are taking Ramelteon. Using Ramelteon with alcohol can lead to serious side effects. Do not drive or operate machinery if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Severe severe interaction
ramelteon+Tobacco
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Tobacco smoke contains substances that may speed the removal of Ramelteon from the body; if you start smoking, Ramelteon may become less effective. Just the opposite occurs when someone stops smoking tobacco; if you stop smoking, the amount of Ramelteon in the blood may increase. Tell your health care professional if you smoke or plan to stop smoking while taking Ramelteon.
Severe severe interaction
frovatriptan+ergotamine
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Avoid the combined use of these drugs within 24 hours of one another. Serious side effects from Serotonin-Receptor Agonists ("Triptans" or drugs used for migraine like Amerge, Axert, Imitrex, Maxalt, Relpax and Zomig) may get worse if you take Ergot Alkaloid related drugs. Taking these two drugs together could potentially lead to chest pain, confusion, loss of coordination, restlessness, sweating, tremor or other side effects. Ask your prescriber about the best approach should you need migraine therapy with a "Triptan" while taking Ergot Alkaloids.
Severe severe interaction
ergotamine+Grapefruit juice
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Taking grapefruit juice with Ergot Alkaloids might increase the risk of nausea, nervousness, chest pain, high blood pressure, palpitations, or other serious side effects, like pain, numbness or reduced circulation to the hands, feet or legs. Ergot Alkaloids include, but are not limited to, Cafergot, Ergotrate, Ergostat, Hydergine, Methergine, Migranal, Sansert or Wigraine. It is best to avoid grapefruit juice while taking Ergot Alkaloids to reduce the chance of Ergot Alkaloid-related side effects.
Severe severe interaction
ergotamine+Tobacco
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It is recommended to avoid nicotine (examples: Nicotine patches or gum) and tobacco while taking any Ergot-type medications. Side effects from Ergot Alkaloids may get worse if you take Nicotine or if you smoke tobacco. Ergot Alkaloids include, but are not limited to, Cafergot, Ergotrate, Ergostat, Hydergine, Methergine, Migranal, Sansert or Wigraine. Side effects might include anxiety, chest pain, numbness in the fingers or toes, tingling, or vision changes.
Severe severe interaction
pyrazinamide+Alcohol
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Drinking alcohol beverages while taking Pyrazinamide, PZA can increase your risk of developing liver problems. It is best to avoid alcohol-containing beverages while taking Pyrazinamide, PZA. Your health care provider will need to do blood tests to check your liver before and during your treatment with Pyrazinamide, PZA. Discuss any new or worsening side effects, such as stomach pain, nausea, vomiting, dark colored urine, or yellowing of eyes or skin, with your health care provider.
Moderate moderate interaction
albuterol+Caffeine-containing Foods/Beverages
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Limit excessive Caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Sympathomimetics and avoid medicines containing additional Caffeine whenever possible. Examples of Sympathomimetics include medicines used to treat asthma and other breathing problems like Albuterol, Arformoterol, Formoterol, Salmterol and others. Taking a high amount of Caffeine with the listed drugs can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, or other side effects.
Moderate moderate interaction
propoxyphene+clemastine
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You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how these drugs affect you. If you notice slurred speech, confusion, severe weakness, or difficulty breathing while taking these drugs, contact your health care provider immediately.
Moderate moderate interaction
propoxyphene+Tobacco
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Tobacco smoking may reduce the effectiveness of Propoxyphene at treating pain, by speeding the removal of Propoxyphene from the body. Alternatively, if you take Propoxyphene e and suddenly stop smoking, you may feel drowsy or more tired, and should not drive or operate machinery until you know how Propoxyphene affects you. If you notice slurred speech, confusion, severe weakness, or difficulty breathing while taking Propoxyphene, contact your health care provider immediately.
Moderate moderate interaction
clemastine+ramelteon
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You may feel drowsy or more tired when taking Anxiolytics, Sedatives, and Hypnotics with Sedating H1 blockers. Do not drive or operate machinery until you know how these drugs affect you.
Moderate moderate interaction
alprostadil+triamterene
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Alprostadil may increase the actions of Antihypertensive Agents. Antihypertensive Agents are drugs used to treat high blood pressure. If the blood pressure drops too low while taking these medications, you may become dizzy or feel faint. To limit this interaction, do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Moderate moderate interaction
epinephrine+Caffeine-containing Foods/Beverages
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Limit excessive Caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Epinephrine and avoid medicines containing additional Caffeine whenever possible. Taking a high amount of Caffeine with Epinephrine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, or other side effects.
Moderate moderate interaction
ramelteon+High Fat Foods
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Taking Ramelteon with food, especially a high fat meal, or immediately after eating may prevent Ramelteon from working. Swallow Ramelteon with some water within 30 minutes before you are ready to go to bed. Tell your health care professional if your sleep problem does not improve or gets worse.
Moderate moderate interaction
sodium bicarbonate+Food
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Avoid taking Sodium Bicarbonate with foods or beverages which contain a high sodium content (such as tomato juice or processed foods). Sodium Bicarbonate contains a significant amount of sodium in the oral solution. Talk to your health care provider about any dietary restrictions which are important in improving your health conditions.
Moderate moderate interaction
triamterene+Alcohol
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Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Minor minor interaction
isotretinoin+Alcohol
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Avoid or limit alcoholic drinks while taking Isotretinoin. Side effects from Isotretinoin may get worse if you also drink alcohol-containing beverages while taking Isotretinoin therapy. In addition, alcohol may alter the results of blood test done to monitor Isotretinoin therapy; avoid alcoholic drinks for at least 36 hours before any orderd blood test.
Minor minor interaction
capecitabine+Food
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Capecitabine should be taken with food.
Minor minor interaction
sodium bicarbonate+ascorbic acid
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Aluminum Hydroxide may decrease the actions of Ascorbic Acid, Vitamin C.
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This feature is for informational purposes only and should not be used to replace the care and information received from your healthcare provider. Please consult a healthcare professional with any health concerns you may have.

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