Severe
phendimetrazine
+ sibutramine
Do not take Sibutramine and phendimetrazine together. Taking Sibutramine with phendimetrazine can increase the risk of high blood pressure, nervousness, palpitations, problems with sleep, or other serious side effects.
Severe
phendimetrazine
+ isosorbide dinitrate
Do not take Nitroglycerin and Sympathomimetics together. Examples of Sympathomimetics include stimulants or weight loss drugs like Amphetamine, Adderall, Dexedrine, Fastin, and Tenuate. Sympathomimetics also include some cough and cold products containing Pseudoephedrine (example Sudafed), Phenylephrine, or Phenylpropanolamine (PPA) and also herbal weight loss products containing ephedra or Ma huang. It is possible Sympathomimetic drugs can cause chest pain, high blood pressure, increased heart rate or other heart-related side effects in persons predisposed to heart conditions, which may counteract (work against) the beneficial effects of Nitroglycerin in treating Chest Pain (Angina or Heart Attack).
Severe
cetirizine
+ Alcohol
Avoid alcohol-containing drinks while taking medicines that cause drowsiness like prescription pain medicines, medications to reduce anxiety, medicines to induce sleep or sedation, and medicines used for colds or allergies. Using some of these drugs along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Severe
rizatriptan
+ sibutramine
Avoid the combined use of these drugs whenever possible. Side effects from Serotonin-Receptor Agonists ("Triptans" used for migraine like Amerge, Axert, Frova, Imitrex, Maxalt, Relpax and Zomig) may get worse if you take Sibutramine and vice-versa. Taking these two drugs together could potentially lead to chest pain, confusion, loss of coordination, restlessness, sweating, tremor, vomiting, or other side effects. Report these or other unusual side effects to your health care provider immediately should they occur.
Severe
risedronate
+ Food
Take Risedronate with water only, on an empty stomach. Taking this drug with food may change how well the drug works for you. It is recommended to take risedronate at least 30 minutes before any other beverage, food or other medication for the day. Avoid laying down for at least 30 minutes after taking this medicine. To avoid irritation to the esophagus (tube connecting mouth to the stomach), this medicine must be taken as directed.
Severe
metronidazole
+ Alcohol
When Alcohol is taken by patients receiving Metronidazole, an extremely unpleasant reaction can occur. This reaction includes flushing, throbbing headache, nausea, vomiting, sweating, thirst, and other effects that may last from 30 minutes to several hours. You should not drink alcoholic beverages or use medicines that contain a large amount of alcohol while taking Metronidazole. Also continue to avoid Alcohol for about 2-3 days after stopping Metronidazole. Interactions with Metronidazole vaginal or topical skin products are not likely.
Severe
metronidazole
+ Food
Most forms of metronidazole may be taken without regard to meals or food. However, extended-release metronidazole tablets, like Flagyl ER, should be taken on an empty stomach 1 hour before or 2 hours after meals. Do not use alcoholic beverages (or take alcohol-containing medicines) while taking or within 2-3 days after stopping Metronidazole to limit the possibility of side effects. When Alcohol is taken by patients receiving Metronidazole, an extremely unpleasant reaction can occur. This reaction includes flushing, throbbing headache, nausea, vomiting, sweating, thirst, and other effects that may last from 30 minutes to several hours. Interactions with Metronidazole vaginal or topical skin products are not likely.
Severe
human papillomavirus vaccine
+ DOXOrubicin
Inform your health care provider you are receiving Chemotherapy before receiving any Vaccine. In general, patients who are undergoing treatment with Antineoplastic Agents (chemotherapy, medicine to treat cancer or other conditions) should not receive Vaccines, including Human Papillomavirus Vaccine, Quadrivalent. The response to the Vaccine may be decreased and side effects to the Vaccine, including infection, may be increased. If you experience fever, chills, or other symptoms of illness, contact your prescriber immediately. Discuss Vaccination options with your health care provider.
Severe
human papillomavirus vaccine
+ infliximab
Inform your health care provider you are taking Infliximab before you receive any Vaccine. Infliximab may decrease the actions of Vaccines. In addition, you may experience increased side effects to the Vaccine if you are taking Infliximab. If you experience fever, chills, or other symptoms of illness, contact your prescriber immediately. Discuss Vaccination options with your health care provider.
Severe
human papillomavirus vaccine
+ fludrocortisone
Inform your health care provider you are taking a Corticosteroid before receiving any Vaccine. In some cases, Vaccines should not be given to persons taking a Corticosteroid for the treatment of a chronic inflammatory health condition like asthma or arthritis. Treatment with Vaccines may result in infection or other side effects in patients receiving Corticosteroids, especially long-term or high dose therapy. Discuss Vaccination options with your health care provider. Also, avoid contact with anyone who has recently received the oral poliovirus vaccine. Topical Corticosteroid products should not interact with Vaccines.
Severe
human papillomavirus vaccine
+ tretinoin oral
Inform your health care provider you are receiving Chemotherapy before receiving any Vaccine. In general, patients who are undergoing treatment with Antineoplastic Agents (chemotherapy, medicine to treat cancer or other conditions) should not receive Vaccines, including Human Papillomavirus Vaccine, Quadrivalent. The response to the Vaccine may be decreased and side effects to the Vaccine, including infection, may be increased. If you experience fever, chills, or other symptoms of illness, contact your prescriber immediately. Discuss Vaccination options with your health care provider.
Severe
DOXOrubicin
+ ASA/carisoprodol/codeine
When prescribed by a doctor, Antineoplastics (medicines to treat cancer) and Salicylates (medicines for fever or pain) are used together sometimes. Check with your doctor before you take any Salicylates while you are taking Antineoplastic therapy. You may bruise or bleed more easily, or you may have kidney problems, if you take these medicines together. Also, Salicylates may hide symptoms of an infection. Many non-prescription products contain Aspirin or other Salicylates; read labels carefully and discuss medicines with your prescriber before taking any medicine while you are on an Antineoplastic therapy.
Severe
sibutramine
+ naratriptan
Avoid the combined use of these drugs whenever possible. Side effects from Serotonin-Receptor Agonists ("Triptans" used for migraine like Amerge, Axert, Frova, Imitrex, Maxalt, Relpax and Zomig) may get worse if you take Sibutramine and vice-versa. Taking these two drugs together could potentially lead to chest pain, confusion, loss of coordination, restlessness, sweating, tremor, vomiting, or other side effects. Report these or other unusual side effects to your health care provider immediately should they occur.
Severe
norfloxacin
+ Calcium-containing foods
Some foods (especially dairy products and other high calcium foods) may decrease the absorption of Norfloxacin from the stomach. Avoid taking Norfloxacin with dairy products such as milk, cheese, and yogurt. Take Norfloxacin on an empty stomach, at least 1 hour before or 2 hours after a meal.
Severe
norfloxacin
+ Foods High in Iron
Some foods (especially dairy products and other high calcium foods) may decrease the absorption of Norfloxacin from the stomach. Avoid taking Norfloxacin with dairy products such as milk, cheese, and yogurt. Take Norfloxacin on an empty stomach, at least 1 hour before or 2 hours after a meal.
Severe
tretinoin oral
+ ASA/carisoprodol/codeine
When prescribed by a doctor, Antineoplastics (medicines to treat cancer) and Salicylates (medicines for fever or pain) are used together sometimes. Check with your doctor before you take any Salicylates while you are taking Antineoplastic therapy. You may bruise or bleed more easily, or you may have kidney problems, if you take these medicines together. Also, Salicylates may hide symptoms of an infection. Many non-prescription products contain Aspirin or other Salicylates; read labels carefully and discuss medicines with your prescriber before taking any medicine while you are on an Antineoplastic therapy.
Severe
isosorbide dinitrate
+ tadalafil
Do not take Phosphodiesterase inhibitors and Nitrates together. Examples of Nitrates include Imdur, Ismo, Isordil, Monoket, Nitrobid, Nitroglycerin, Nitrostat, and others. Phosphodiesterase inhibitors include Viagra, Cialis and Levitra. This interaction may cause dangerously low blood pressure, which can lead to life-threatening side effects, like fainting, palpitations, heart attack or stroke.
Severe
eszopiclone
+ Alcohol
Avoid alcohol-containing drinks while taking medicines that cause drowsiness like prescription pain medicines, medications to reduce anxiety, medicines to induce sleep or sedation, and medicines used for colds or allergies. Using some of these drugs along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Severe
ASA/carisoprodol/codeine
+ Alcohol
Side effects from Salicylates (such as Aspirin, ASA, Doan's Pills, Trilisate, or Disalcid) may get worse if you drink alcohol-containing drinks. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. Avoid alcohol containing drinks while taking aspirin. Alcohol intake should be limited even with short term use of Salicylates.
Severe
ASA/carisoprodol/codeine
+ Alcohol
Avoid alcohol-containing drinks while taking medicines that cause drowsiness like prescription pain medicines, medications to reduce anxiety, medicines to induce sleep or sedation, and medicines used for colds or allergies. Using some of these drugs along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Moderate
phendimetrazine
+ caffeine
Limit caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Phendimetrazine. Also avoid medicines containing additional Caffeine whenever possible. Side effects from Phendimetrazine may get worse if you take excessive Caffeine. Taking a high amount of Caffeine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, tremor, or other side effects.
Moderate
phendimetrazine
+ Alcohol
Side effects from Phendimetrazine such as dizziness, lightheadedness, fainting, or confusion may get worse if you consume alcohol-containing products.
Moderate
phendimetrazine
+ Caffeine-containing Foods/Beverages
Limit caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Phendimetrazine. Also avoid medicines containing additional Caffeine whenever possible. Side effects from Phendimetrazine may get worse if you take excessive Caffeine. Taking a high amount of Caffeine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, tremor, or other side effects.
Moderate
cetirizine
+ eszopiclone
You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how these drugs affect you.
Moderate
cetirizine
+ ASA/carisoprodol/codeine
You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how these drugs affect you. If you notice slurred speech, confusion, severe weakness, or difficulty breathing while taking these drugs, contact your health care provider immediately.
Moderate
melatonin
+ eszopiclone
Do not take Melatonin and Anxiolytics, Sedatives, and Hypnotics (drugs to relieve anxiety or to cause drowsiness or sleep) together without talking to your health care provider. Generally it is recommended that you do not take two drugs for sleep together. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how these drugs affect you.
Moderate
sibutramine
+ ASA/carisoprodol/codeine
While the risk is low, there may be a potential to develop stomach irritation and bleeding if Aspirin, ASA and Sibutramine are given together on a regular basis. However, more study is needed to understand this potential interaction. Your prescriber may decide that the regular use of Aspirin along with Sibutramine is right for you. Discuss your drug regimen with your health care provider if you have questions regarding this combination. Many over-the-counter medications that do not require a prescription may also contain Aspirin. Ask your pharmacist or other health care provider if you are not sure if an over-the-counter medication contains aspirin. Report stomach irritation that continues to be bothersome, or any signs of bleeding (like unusual dark tarry stools) to your health care provider.
Moderate
sibutramine
+ Grapefruit juice
Side effects from Sibutramine may get worse if you take grapefruit juice. Common side effects of Sibutramine include constipation, difficulty sleeping or restlessness, dry mouth, headache, and loss of appetite. Report these effects if they are troublesome. Do not significantly alter your intake of grapefruit juice or grapefruit while taking Sibutramine. Sibutramine does not interact with other foods.
Moderate
sibutramine
+ Alcohol
You may wish to limit your alcoholic beverage intake while on sibutramine. Alcoholic beverages are high in calories and may impede weight loss. Also, Alcohol may cause dizziness or drowsiness when used in combination with Sibutramine. Do not drive or operate machinery until you know how these drugs affect you.
Moderate
norfloxacin
+ tretinoin oral
You may be more sensitive (increased chance of sunburn or other skin reaction) to sunlight or tanning beds while using Retinoids and 'Quinolone' antibiotics (examples: Cipro, Floxin, Levaquin, Tequin) together. While taking these drugs together, keep out of the sun, or wear protective clothing outdoors and use a sunscreen. Do not use sun lamps or tanning beds or booths.
Moderate
norfloxacin
+ Caffeine-containing Foods/Beverages
Although an interaction is possible, these drugs are often used together. Side effects from Caffeine may get worse if you take Norfloxacin. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. You may need to limit your Caffeine intake. Common foods and beverages containing caffeine include coffee, teas, colas and chocolate. Many non-prescription drugs and diet aids may also contain caffeine.
Moderate
fludrocortisone
+ ASA/carisoprodol/codeine
Although an interaction is possible, these drugs may be used together for short periods of time. Side effects from Salicylates (examples: Aspirin, Doan's Pills, Trilisate, Dolobid, or Disalcid) such as stomach upset, nausea, or heartburn may get worse or more serious side effects such as ulcers may occur if you also take Betamethasone, especially if taken together for prolonged periods of time. Many non-prescription products contain Salicylates; closely read labels before taking any medicines with Betamethasone. Skin products containing Betamethasone should not interact with Salicylates.
Moderate
tretinoin oral
+ Alcohol
Your skin may be more sensitive if you use Tretinoin skin products and also are applying products that contain alcohol (ethanol) to your skin. Do not use alcohol-containing skin products and Tretinoin skin products together without talking to your health care provider. If these products are used together, report any excessive skin irritation, dryness, or redness.
Moderate
isosorbide dinitrate
+ Alcohol
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Moderate
tadalafil
+ Grapefruit juice
Grapefruit juice and grapefruit-containing foods may increase the side effects of Tadalafil (Cialis). Do not significantly alter grapefruit juice intake while taking this drug, or avoid grapefruit juice if possible. When taking Cialis, contact your prescriber immediately if you experience chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your usual heart beat (fast, slow, or irregular heart beat).
Moderate
tadalafil
+ Alcohol
Do not drink Alcohol to excess (examples, 5 glasses of wine or 5 shots of whiskey) when taking Tadalafil. When taken in excess, Alcohol can increase your chances of getting a headache or getting dizzy, increasing your heart rate or lowering your blood pressure.
Moderate
eszopiclone
+ ASA/carisoprodol/codeine
You may feel drowsy or more tired when taking these drugs together. This effect may last for a few days after you stop taking these drugs together. Do not drive or operate machinery until you know how these drugs affect you. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Moderate
caffeine
+ Grapefruit juice
Side effects from Caffeine may get worse if you take Grapefruit juice or other foods that contain significant amounts of Grapefruit. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. Do not significantly alter your grapefruit juice intake while taking medicines containing caffeine.
Moderate
caffeine
+ Tobacco
Tobacco smoke contains substances that may speed the removal of Caffeine from the body. If you start smoking Caffeine may become less effective. Tobacco smokers often drink several caffeinated beverages daily. Just the opposite occurs when someone stops smoking tobacco; if you stop smoking this may increase the amount of Caffeine in the blood and side effects from Caffeine may get worse. Too much Caffeine can cause nausea, nervousness, or sleeplessness, and occasionally other effects like tremor. If you stop smoking tobacco, you may need to lower your Caffeine intake.
Moderate
caffeine
+ Caffeine-containing Foods/Beverages
While taking Caffeine products, limit the use of foods, beverages, herbs and other medicines that contain additional caffeine, like coffee, teas, colas, chocolate and some diet pills. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. Some drug products for adults that contain caffeine have about as much caffeine as a cup of coffee.
Moderate
ASA/carisoprodol/codeine
+ Alcohol
Do not drink Alcoholic beverages while taking Carisoprodol (Rela, Soma). You may feel drowsy or more tired or other more serious side effects (excessive sedation, confusion, difficulty staying alert, or seizures) may occur if you drink alcohol-containing drinks while taking Carisoprodol.
Minor
cetirizine
+ desloratadine
Although an interaction is possible, these drugs are often used together. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how these drugs affect you.
Minor
risedronate
+ ASA/carisoprodol/codeine
These drugs are sometimes used together. However, you may be more likely to develop stomach or esophagus irritation from Risedronate if you also take Salicylates (examples: Aspirin, Trilisate, Doan's Pills, or Dolobid). Promptly report any stomach or throat irritation or other related side effects that are bothersome.
Minor
esomeprazole
+ ASA/carisoprodol/codeine
Side effects from Carisoprodol may get worse if you take Esomeprazole. In theory, Esomeprazole can lead to decreased elimination of Carisoprodol from the body. While taking Carisoprodol, report extreme drowsiness, confusion, a slowed rate of breathing or other new or unusual side effects to your health care provider. Although an interaction is possible, these drugs might still be used together. Do not drive or operate machinery until you know how these drugs affect you.
Minor
desloratadine
+ ASA/carisoprodol/codeine
Although an interaction is possible, these drugs are often used together. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how these drugs affect you.
Minor
amoxicillin-clavulanate
+ ASA/carisoprodol/codeine
Although an interaction is possible, these drugs are often used together. There is an possiblity of increased side effects from Aspirin, ASA or Penicillins (medicines for infection, examples: Amoxi, amoxicillin, ampicillin, Omnipen, Pen-Vee, Veetids), such as dizziness, drowsiness, lightheadedness, nausea, vomiting when these drugs are taken together.
Minor
DOXOrubicin
+ fludrocortisone
Although an interaction is possible, these drugs are often used together. Additive benefits may occur when Corticosteroids (examples: Dexamethasone, Methylprednisolone, Prednisone, or Prednisolone) and Antineoplastic Agents (chemotherapy, medicine used to treat cancer and other conditions) are used together. The combined therapies are often designed to take advantage of these benefits. However, some side effects may include an increased risk of infection. If you notice signs or symptoms of an infection, such as a fever, sore throat, etc., do not treat yourself and seek your prescriber's evaluation and advice.
Minor
naratriptan
+ Tobacco
Tobacco smoking results in a speedier removal of naratriptan from the body. However, it is not expected that this interaction will affect naratriptan's efficacy in treating migraines. Tobacco smoking can be a risk factor for heart and vascular disease; check with your doctor regarding quitting smoking if you are a frequent migraine sufferer.
Minor
fludrocortisone
+ tretinoin oral
Although an interaction is possible, these drugs are often used together. Additive benefits may occur when Corticosteroids (examples: Dexamethasone, Methylprednisolone, Prednisone, or Prednisolone) and Antineoplastic Agents (chemotherapy, medicine used to treat cancer and other conditions) are used together. The combined therapies are often designed to take advantage of these benefits. However, some side effects may include an increased risk of infection. If you notice signs or symptoms of an infection, such as a fever, sore throat, etc., do not treat yourself and seek your prescriber's evaluation and advice.
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