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  • Basic Info
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Generic: tolvaptan
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It is used to treat low levels of sodium in the blood.

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What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • clarithromycin
  • delavirdine
  • dalfopristin; quinupristin
  • indinavir
  • isoniazid
  • itraconazole
  • ketoconazole
  • nefazodone
  • nelfinavir
  • ritonavir
  • saquinavir
  • telithromycin
  • tipranavir

This medicine may also interact with the following medications:

  • aprepitant
  • cyclosporine
  • digoxin
  • diuretics
  • erythromycin
  • grapefruit juice
  • medicines for blood pressure
  • medicines for seizures like carbamazepine, phenobarbital, phenytoin
  • medicines for tuberculosis like rifampin, rifabutin, and rifapentine
  • some medicines for fungal infections like fluconazole, miconazole, voriconazole
  • St. John's Wort

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

To prevent dehydration, have water available to drink at all times while taking this medicine. Drink when you are thirsty, unless your doctor or healthcare professional tells you otherwise.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • black or tarry stools
  • chest pain
  • confusion
  • fast, irregular heartbeat
  • mood changes
  • seizures
  • trouble speaking
  • uncontrollable body movements
  • unusually weak or tired
  • vomiting blood

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation
  • dry mouth
  • increased hunger or thirst
  • increased urination

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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