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  • Basic Info
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Generic: tacrolimus
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It is used to decrease the immune system's response to a transplanted organ.
               



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What is this medicine?

TACROLIMUS (ta KROE li mus) is used to decrease the immune system's response to a transplanted organ.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • heart disease or heart failure
  • high blood pressure
  • immune system problems
  • infection
  • kidney disease
  • liver disease
  • an unusual or allergic reaction to tacrolimus, lactose, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. If you take the medicine with food, always take it with food. Do not take the medicine with grapefruit juice. Follow the directions on the prescription label. Take your medicine at regular intervals. You must take the medicine at the same time each day. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can, and call your doctor or health care professional. Call your doctor or health care professional if you vomit after a dose.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • astemizole
  • cidofovir
  • cisapride
  • cyclosporine
  • droperidol
  • grepafloxacin
  • pimozide
  • probucol
  • ziprasidone

This medicine may also interact with the following medications:

  • alcohol and medicines that contain alcohol
  • amiodarone
  • amphotericin B
  • antacids
  • antibiotics like aminoglycosides, chloramphenicol, clarithromycin, erythromycin, and troleandomycin
  • bromocriptine
  • calcium channel blockers like diltiazem, nicardipine, nifedipine, and verapamil
  • cisplatin
  • danazol
  • diuretics
  • ethinyl estradiol
  • ganciclovir
  • grapefruit juice
  • medicines for fungal infections like amphotericin B, caspofungin, clotrimazole, fluconazole, itraconazole, ketoconazole, posaconazole, and voriconazole
  • medicines for seizures like carbamazepine, phenobarbital, and phenytoin
  • medicines for stomach problems like cimetidine, famotidine, lansoprazole, and omeprazole
  • metoclopramide
  • nefazodone
  • protease inhibitors like bocepravir, nelfinavir, ritonavir, and telaprevir
  • rifabutin
  • rifampin
  • sirolimus
  • St. John's wort
  • steroid medicines like prednisone, cortisone, and methylprednisone
  • troleandomycin
  • vaccines

               
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