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What is this medicine?

SULFAMETHOXAZOLE; TRIMETHOPRIM or SMX- TMP (suhl fuh meth OK suh zohl; trye METH oh prim) is a combination of a sulfonamide antibiotic and a second antibiotic, trimethoprim. It is used to treat or prevent certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • anemia
  • asthma
  • being treated with anticonvulsants
  • if you frequently drink alcohol containing drinks
  • kidney disease
  • liver disease
  • low level of folic acid or glucose- 6- phosphate dehydrogenase
  • poor nutrition or malabsorption
  • porphyria
  • severe allergies
  • thyroid disorder
  • an unusual or allergic reaction to sulfamethoxazole, trimethoprim, sulfa drugs, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not skip doses or stop your medicine early.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. This medicine has been used in children as young as 2 months of age.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • aminobenzoate potassium
  • dofetilide
  • metronidazole

This medicine may also interact with the following medications:

  • ACE inhibitors like benazepril, enalapril, lisinopril, and ramipril
  • cyclosporine
  • digoxin
  • diuretics
  • indomethacin
  • medicines for diabetes
  • methenamine
  • methotrexate
  • phenytoin
  • potassium supplements
  • pyrimethamine
  • sulfinpyrazone
  • tricyclic antidepressants
  • warfarin

               
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