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  • Basic Info
Licensed from
Generic: st. john's wort
an herbal product - treats Seasonal affective disorder, Peri-menopausal symptoms, Human immunodeficiency virus, Nerve pain, Premenstrual syndrome, Anxiety disorder, Social phobia, Depressive disorder, Atopic dermatitis, Somatoform disorders, and Obsessive-compulsive disorder

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WARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.


Adults (over 18 years old)

Clinical trials have used a range of doses, including 0.17- 2.7 milligrams of hypericin by mouth, and 900- 1,800 milligrams of St. John's wort extract daily by mouth.

1.5% hyperforin (verum) has been applied to the skin for the treatment of atopic dermatitis.

Children (under 18 years old)

There is not enough scientific data to recommend St. John's wort in children.


DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.


Infrequent allergic skin reactions, including rash and itching, are reported in human studies.

Side Effects and Warnings

In published studies, St. John's wort has generally been well tolerated at recommended doses for up to 1- 3 months. The most common adverse effects include gastrointestinal upset, skin reactions, fatigue/ sedation, restlessness or anxiety, sexual dysfunction (including impotence), dizziness, headache, and dry mouth. Several recent studies suggest that side effects occur in one to three percent of patients taking St. John's wort, and that the number of adverse events may be similar to placebo (and less than standard antidepressant drugs). Animal toxicity studies have found only non- specific symptoms such as weight loss. One small study reported elevated thyroid stimulating hormone (TSH) levels to be associated with taking St. John's wort.

It has been reported that St. John's wort may cause psychiatric symptoms such as suicidal and homicidal thoughts.

Delayed ejaculation has been reported in animal studies.

Pregnancy and Breastfeeding

There is not enough scientific evidence available to recommend use during pregnancy or breastfeeding.

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