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  • Basic Info
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Generic: st. john's wort
JOHN'S WORT (seynt JONZ wurt) is an herbal or dietary supplement

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What is this medicine?

ST. JOHN'S WORT (seynt JONZ wurt) is an herbal or dietary supplement. It is promoted to help improve depressed moods. The FDA has not approved this supplement for any medical use.

This supplement may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • heart disease
  • high blood pressure
  • immune system problems
  • kidney disease
  • liver disease
  • mental problems like anxiety, depression, mania
  • stroke
  • suicidal thoughts or history of attempted suicide
  • taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
  • an unusual or allergic reaction to St. John's wort, other herbs, plants, medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this herb by mouth with a glass of water. Follow the directions on the package labeling, or talk to your health care professional for advice. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this herb in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • amiodarone
  • bosentan
  • cyclosporine
  • digoxin
  • female hormones, like estrogens or progestins and birth control pills
  • irinotecan
  • linezolid
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for blood pressure or heart disease
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for HIV infection
  • medicines for sleep during surgery
  • methylene blue
  • sirolimus
  • sunitinib
  • tacrolimus
  • theophylline
  • warfarin

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