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  • Basic Info
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Generic: rifapentine
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It is used to treat of tuberculosis (TB)

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What is this medicine?

RIFAPENTINE (RIF a pen teen) is an antibiotic. It is used to treat of tuberculosis (TB). This medicine is never used alone for tuberculosis, but in combination with at least one other agent.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • immune system problems
  • liver disease
  • an unusual or allergic reaction to rifapentine, rifabutin, rifampin, other medicines, foods, dyes or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. If this medicine upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the TB resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years old for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • medicines for HIV
  • voriconazole

This medicine may also interact with the following medications:

  • antifungal medicines like fluconazole, itraconazole, ketoconazole
  • barbituates, like phenobarbital
  • birth control pills
  • clofibrate
  • cyclosporine
  • levothyroxine
  • medicines that treat or prevent blood clots like warfarin
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • oral medicines for diabetes
  • quinine
  • sildenafil
  • some antibiotics like chloramphenicol, clarithromycin, dapsone, doxycycline, ciprofloxacin
  • some medicines for heart rhythm problems like disopyramide, mexiletine, quinidine, tocainide
  • some heart medicines like digoxin, diltiazem, nifedipine, verapamil
  • some medicines for seizures like phenytoin
  • some prescription pain medications like methadone
  • steroid medicines like prednisone or cortisone
  • tacrolimus
  • theophylline

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