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  • Basic Info
Licensed from
Generic: rhubarb preparation
treats Obesity, Gastrointestinal tract disorders, Renal failure, Hepatitis, Herpes, Sepsis, Nasopharyngeal carcinoma, Gingivitis, Nephritis, Pre-eclampsia, Gastrointestinal cancer surgery, Bleeding, Constipation, Hemorrhagic fever, Fatty liver, Aplastic anemia, Hypercholesterolemia, and Age-associated memory impairment

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This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Rebecca Bramwell, PharmD (Northeastern University); Nicole Giese, MS (Natural Standard Research Collaboration); Sayuri Fujita, PharmD (Massachusetts College of Pharmacy); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Albrecht UW. [The efficacy and tolerability of Pyralvex solution and Pyralvex Gel in the treatment of gingivitis. Results of double- blind, randomised, controlled clinical trials]. Der Freie Zahnarzt 1997;9:76- 80.

Cai J, Xuan ZR, Wei YP, et al. [Effects of perioperative administration of Rhubarb on acute inflammatory response in patients with gastric cancer]. Zhong.Xi.Yi.Jie.He.Xue.Bao. 2005;3(3):195- 198.

Deng YY, Chen YP, Wang L, et al. [Clinical study on treatment of mid- advanced crescentic nephritis by qingre huoxue recipe]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2004;24(12):1084- 1086.

Fan JG. Evaluating the efficacy and safety of Danning Pian in the short- term treatment of patients with non- alcoholic fatty liver disease: a multicenter clinical trial. Hepatobiliary.Pancreat.Dis.Int 2004;3(3):375- 380.

Fu DC, Yu CY. [Observation on therapeutic effect of Rhubarb and sanchi powder in treating patients with hemorrhagic fever in nephrotic syndrome complicated with digestive tract bleeding]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2005;25(8):744- 747.

Greenway FL, Liu Z, Martin CK, et al. Safety and efficacy of NT, an herbal supplement, in treating human obesity. Int J Obes (Lond) 4- 25- 2006;

Ho TY, Wu SL, Chen JC, et al. Emodin blocks the SARS coronavirus spike protein and angiotensin- converting enzyme 2 interaction. Antiviral Res 5- 15- 2006.

Li C, Zhou J, Gui P, He X. Protective effect of rhubarb on endotoxin- induced acute lung injury. J Tradit.Chin Med 2001;21(1):54- 58.

Pelletier JP, Yaron M, Haraoui B, et al. Efficacy and safety of diacerein in osteoarthritis of the knee: a double- blind, placebo- controlled trial. The Diacerein Study Group. Arthritis Rheum 2000;43(10):2339- 2348.

Peng SM, Wang SZ, Zhao JP. [Effect of rhubarb on inflammatory cytokines and complements in patients with systemic inflammation reaction syndrome and its significance]. Zhongguo

Zhong.Xi.Yi.Jie.He.Za Zhi. 2002;22(4):264- 266.

Sauro S, Gandolfi MG, Prati C, et al. Oxalate- containing phytocomplexes as dentine desensitisers: An in vitro study. Arch Oral Biol 4- 5- 2006;

Tseng SH, Lee HH, Chen LG, et al. Effects of three purgative decoctions on inflammatory mediators. J Ethnopharmacol. 4- 21- 2006;105(1- 2):118- 124.

Yan M, Zhang LY, Sun LX, et al. Nephrotoxicity study of total rhubarb anthraquinones on Sprague Dawley rats using DNA microarrays. J Ethnopharmacol. 4- 15- 2006;

Zhou Y, Huang Z, Huang T, et al. Clinical study of shengxue mixture in treating aplastic anemia. Chinese Journal of Integrated Traditional and Western Medicine 2001;7(3):186- 189.

Zhu W, Wang XM, Zhang L, et al. Pharmacokinetic of rhein in healthy male volunteers following oral and retention enema administration of rhubarb extract: a single dose study. Am J Chin Med 2005;33(6):839- 850.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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