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  • Basic Info
Licensed from
Generic: trans-resveratrol
treats Cancer and Cardiovascular disease

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This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration ( Julie Conquer, PhD (Natural Standard Research Collaboration); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Nicole Giese, MS (Natural Standard Research Collaboration); Dana A. Hackman, BS (Northeastern University); Brian Szczechowski, PharmD (Massachusetts College of Pharmacy); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration); Shannon Welch, PharmD (Northeastern University); Denise Wong, PharmD (Northeastern University).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Aggarwal BB, Shishodia S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol 2006 May 14;71(10):1397- 421.

Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006 Jun;5(6):493- 506.

Cheong H, Ryu SY, Kim KM. Anti- allergic action of resveratrol and related hydroxystilbenes. Planta Med 1999;65(3):266- 268.

Cruz MN, Luksha L, Logman H, et al. Acute responses to phytoestrogens in small arteries from men with coronary heart disease. Am J Physiol Heart Circ Physiol 2006 May;290(5):H1969- 75.

Delmas D, Lancon A, Colin D, et al. Resveratrol as a chemopreventive agent: a promising molecule for fighting cancer. Curr Drug Targets 2006 Apr;7(4):423- 42.

Gronbaek M, Deis A, Sorensen TI, et al. Mortality associated with moderate intakes of wine, beer, or spirits. BMJ 5- 6- 1995;310(6988):1165- 1169.

Labinskyy N, Csiszar A, Veress G, et al. Vascular dysfunction in aging: potential effects of resveratrol, an anti- inflammatory phytoestrogen. Curr Med Chem 2006;13(9):989- 96.

Lekakis J, Rallidis LS, Andreadou I, et al. Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease. Eur J Cardiovasc Prev Rehabil 2005 Dec;12(6):596- 600.

Levi F, Pasche C, Lucchini F, et al. Resveratrol and breast cancer risk. Eur.J Cancer Prev 2005;14(2):139- 142.

Rainsford KD. Influenza ("Bird Flu"), inflammation and anti- inflammatory/ analgesic drugs. Inflammopharmacology. 2006 Mar;14(1- 2):2- 9.

Rahman I, Kilty I. Antioxidant therapeutic targets in COPD. Curr Drug Targets 2006 Jun;7(6):707- 20.

Rakici O, Kiziltepe U, Coskun B, et al. Effects of resveratrol on vascular tone and endothelial function of human saphenous vein and internal mammary artery. Int J Cardiol 2005 Nov 2;105(2):209- 15.

Truelsen T, Gronbaek M, Schnohr P, et al. Intake of beer, wine, and spirits and risk of stroke: the Copenhagen city heart study. Stroke 1998;29(12):2467- 2472.

Zern TL, Wood RJ, Greene C, et al Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress. J Nutr 2005;135(8):1911- 1917.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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