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  • Basic Info
Licensed from
Generic: pycnogenol
a nutraceutical product - treats Platelet aggregation, Erectile dysfunction, High blood pressure, Melasma, Asthma, Cramps, Edema, Gingival bleeding / plaque, Diabetes, Male infertility, Attention deficient hyperactivity disorder, Diabetic microangiopathy, Dysmenorrhea, High cholesterol, Migraine, Retinopathy, Sunburn, Menopausal symptoms, Venous leg ulcers, Antioxidant, Systemic lupus erythematosus, and Chronic venous insufficiency and prevents Prevention of blood clots/edema during long airplane fights

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WARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.


Adults (18 years and older)

In general, 25- 360 milligrams has been taken by mouth in divided doses daily. For gum health, 5 milligrams Pycnogenol® in chewing gum for 14 days has been used.

Pycnogenol® appears to be absorbed into the bloodstream in about 20 minutes. Once absorbed, therapeutic effects are purported to last for approximately 72 hours, followed by excretion in the urine. Because of its astringent taste and occasional minor stomach discomfort, it may be best to take Pycnogenol® with or after meals

Children (younger than 18 years)

Due to insufficient data, Pycnogenol® is not recommended for use in children.


DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.


Individuals should not take Pycnogenol® if allergic to it or any of its components.

Side Effects and Warnings

Pycnogenol® is generally reported as being well tolerated. Low acute and chronic toxicity with mild unwanted effects may occur in a small percentage of patients following oral administration. Because of its astringent taste and occasional minor stomach discomfort, it may be best to take Pycnogenol® with or after meals. To date, no serious adverse effects have been reported in the available scientific literature, although systematic study of safety is not available.

In theory, Pycnogenol® may alter blood sugar levels. Caution is advised in patients with diabetes or hypoglycemia and in those taking drugs, herbs, or supplements that affect blood sugar. Serum glucose levels may need to be monitored by a healthcare provider, and medication adjustments may be necessary.

In theory, Pycnogenol® may increase the risk of bleeding. Caution is advised in patients with bleeding disorders or taking drugs that may increase the risk of bleeding. Dosing adjustments may be necessary.

Pregnancy & Breastfeeding

Pycnogenol® is not recommended during pregnancy or breastfeeding due to lack of scientific evidence.

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