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  • Basic Info
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Generic: peppermint oil
an herbal product - treats Urinary tract infection, Abdominal distention, Cough, Asthma, Bad breath, Antispasmodic, Irritable bowel syndrome, Vigilance improvement in brain injury, Nasal congestion, Functional bowel disorders, Post-herpetic neuralgia, Tension headache, Nausea, Breast tenderness, Tuberculosis, Indigestion, and Stroke recovery
               



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Interactions

Interactions with Drugs

Peppermint oil by mouth may increase blood levels of the drugs felodipine (Plendil®) and simvastatin (Zocor®). Peppermint oil increases levels of cyclosporine in the blood. Peppermint oil used on the skin with 5- fluorouracil (5- FU) may increase the rate of absorption of 5- FU.

Peppermint oil may interfere with the way the body processes certain drugs using the liver's "cytochrome P450" enzyme system. As a result, the levels of these drugs may be increased in the blood and may cause increased effects or potentially serious adverse reactions. Patients using these medications should check the package insert and speak with a qualified healthcare provider including a pharmacist about possible interactions.

Peppermint may also interact with antacids, other calcium channel blockers, or drugs that lower high blood pressure. Caution is advised.

Interactions with Herbs and Supplements

Peppermint oil may interfere with the way the body processes certain herbs or supplements using the liver's "cytochrome P450" enzyme system. As a result, the levels of other herbs or supplements may be too high in the blood. It may also alter the effects that other herbs or supplements possibly have on the P450 system. Patients using these medications should check the package insert and speak with a qualified healthcare provider including a pharmacist about possible interactions.

Peppermint may also interact with herbs and supplements that raise or lower blood pressure or have antacid properties. Caution is advised.

Attribution

This information is based on a professional level monograph edited and peer- reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Tracee Rae Abrams, PharmD (University of Rhode Island); Ethan Basch, MD (Memorial Sloan- Kettering Cancer Center); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Nicole Giese, MS (Natural Standard Research Collaboration); Mary Giles, PharmD (University of Rhode Island); David Keifer, MD (University of Arizona); Catherine DeFranco Kirkwood, MPH, CCCJS- MAC (MD Anderson Cancer Center); Michelle Miranda, PharmD (University of Rhode Island); Adrianne Rogers, MD (Harvard Medical School); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration); Jen Woods, BS (Northeastern University).

               
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