Generic: Organic germanium
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Interactions with Drugs
Vitamin O products may contain sodium chloride (salt); therefore, patients with high blood pressure should be aware. Use cautiously if taking blood pressure- lowering agents due to possible additive effects.
Interactions with Herbs & Dietary Supplements
Vitamin O products may contain sodium chloride (salt); therefore, patients with high blood pressure should be aware. Use cautiously if taking blood pressure- lowering herbs or supplements due to possible additive effects.
This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Sarah Elsabagh, BSc, PhD (King's College, University of London); Nicole Giese, MS (Natural Standard Research Collaboration); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).
BibliographyDISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Asaka T, Nitta E, Makifuchi T, et al. Germanium intoxication with sensory ataxia. J.Neurol.Sci. 1995;130(2):220- 223.
Fujimoto M, Ishibashi H, Shimamura R, et al. [A patient with liver cirrhosis manifesting various symptoms including cerebellar ataxia due to germanium intoxication]. Fukuoka Igaku Zasshi 1992;83(3):139- 143.
Iijima M, Mugishima M, Takeuchi M, et al. [A case of inorganic germanium poisoning with peripheral and cranial neuropathy, myopathy and autonomic dysfunction]. No To Shinkei 1990;42(9):851- 856.
Kamijo M, Yagihashi S, Kida K, et al. [An autopsy case of chronic germanium intoxication presenting peripheral neuropathy, spinal ataxia, and chronic renal failure]. Rinsho Shinkeigaku 1991;31(2):191- 196.
Krapf R, Schaffner T, Iten PX. Abuse of germanium associated with fatal lactic acidosis. Nephron 1992;62(3):351- 356.
Nagata N, Yoneyama T, Yanagida K, et al. Accumulation of germanium in the tissues of a long- term user of germanium preparation died of acute renal failure. J.Toxicol.Sci. 1985;10(4):333- 341.
Obara K, Saito T, Sato H, et al. Germanium poisoning: clinical symptoms and renal damage caused by long- term intake of germanium. Jpn.J.Med. 1991;30(1):67- 72.
Raisin J, Hess B, Blatter M, et al. [Toxicity of an organic Germanium compound: deleterious consequences of a "natural remedy"]. Schweiz.Med.Wochenschr. 1- 8- 1992;122(1- 2):11- 13.
Schroeder HA, Balassa JJ. Abnormal trace metals in man: germanium. J.Chronic.Dis. 1967;20(4):211- 224.
Takeuchi A, Yoshizawa N, Oshima S, et al. Nephrotoxicity of germanium compounds: report of a case and review of the literature. Nephron 1992;60(4):436- 442.
Van der Spoel JI, Stricker BH, Schipper ME, et al. [Toxic damage of kidney, liver and muscle attributed to the administration of germanium- lactate- citrate]. Ned.Tijdschr.Geneeskd. 6- 22- 1991;135(25):1134- 1137.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.