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  • Basic Info
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Generic: octacosanol
treats Amyotrophic lateral sclerosis
               



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Category

Herbs & Supplements

Synonyms

1- octacosanol, (3)H- octacosanol, cluytyl alcohol, montanyl alcohol, n- octacosanol, octacosanoic acid, policosanol, Suregada angustifolia (Baill. ex Muell. Arg.), very long chain fatty alcohols.

Background

Policosanol is a mixture of very long chain alcohols that is purified from sugar cane wax. Approximately 67% of policosanol is octacosanol. Although some research has been conducted using policosanol, little research is currently available that focuses on octacosanol alone. One preliminary clinical study in amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease- a chronic, progressive, neurologic disease in which loss of nerve cells produces muscle paralysis) patients showed no measurable benefit from octacosanol. As octacosanol is the main component of policosanol, more research is needed to determine if octacosanol is the primary active component of policosanol.

Evidence

DISCLAIMER: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.

Amyotrophic lateral sclerosis (ALS): ALS or Lou Gehrig's disease is a chronic, progressive, neurologic disease in which loss of nerve cells produces muscle paralysis. Preliminary study does not show any evidence of benefit in neurologic (brain) or pulmonary (lung) symptoms of amyotropic lateral sclerosis (ALS) patients. Additional study is needed in this area.
Grade: D

Tradition

WARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Adrenoleukodystrophy (ALD, a rapidly progressive X- linked genetic degenerative disorder), antibacterial, antioxidant, atherosclerosis (hardening of the arteries), cardiovascular health, coronary heart disease, fatigue, granuloma annulare (chronic skin condition), hyperlipidemia (high cholesterol), hypertension (high blood pressure), intermittent claudication (muscle pain), ischemic heart disease, liver damage from drugs or toxins, neurologic disorders (Sjogren- Larsson syndrome), osteoporosis (postmenopausal), Parkinson's disease, platelet aggregation inhibition (blood disorder), reactivity/ brain activity, seizure disorder, stroke prevention.
               
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