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  • Basic Info
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Generic: mephobarbital
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It is used to help you sleep or to help control seizures

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What is this medicine?

MEPHOBARBITAL (me foe BAR bi tal) is a barbiturate. It is used to help you sleep or to help control seizures.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • depression
  • drug abuse or addiction
  • history of suicide attempt
  • if you frequently drink alcohol containing drinks
  • kidney disease
  • liver disease
  • lung or breathing disease, like asthma
  • porphyria
  • suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
  • an unusual or allergic reaction to mephobarbital, phenobarbital, other medicines, lactose, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • alcohol
  • other barbiturates
  • voriconazole

This medicine may also interact with the following medications:

  • antihistamines
  • certain medicines for seizures like phenytoin, valproic acid
  • doxycycline
  • female hormones, like estrogens or progestins and birth control pills
  • griseofulvin
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • other medicines that cause drowsiness, sleep
  • steroid medicines like prednisone or cortisone
  • warfarin

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