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  • Basic Info
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Generic: maprotiline
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It is used to treat depression
               



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What is this medicine?

MAPROTILINE (ma PROE ti leen) is used to treat depression. This medicine also helps to relieve anxiety associated with depression.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bipolar disorder
  • blood disorders
  • heart disease
  • liver disease
  • previous heart attack
  • seizures
  • suicidal thoughts or family history of suicide
  • an unusual or allergic reaction to maprotiline, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition may worsen.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • cisapride
  • cocaine
  • droperidol
  • halofantrine
  • levomethadyl
  • linezolid
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for mental depression
  • medicines to control heart rhythm
  • methylene blue
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • pimozide
  • sparfloxacin
  • St. John's Wort
  • ziprasidone

This medicine may also interact with the following medications:

  • barbiturates, like phenobarbital
  • cimetidine
  • medicines for anxiety or sleeping problems, such as diazepam or temazepam
  • medicines for colds and breathing difficulties
  • medicines for hay fever and other allergies
  • medicines for high blood pressure
  • medicines for the thyroid
  • phenytoin

               
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