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  • Basic Info
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Generic: locust bean gum
treats Diarrhea in children, Gastroesophageal reflux disease, and Hypercholesterolemia

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This information is based on a systematic review of scientific literature edited and peer- reviewed by contributors to the Natural Standard Research Collaboration ( Thomas Brendler (PlantaPhile); Nicole Giese, MS (Natural Standard Research Collaboration); Joerg Gruenwald, PhD (Phytopharm Research); David Lee, PharmD (Massachusetts College of Pharmacy); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Aggett PJ, Agostoni C, Goulet O, et al. Antireflux or antiregurgitation milk products for infants and young children: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol. Nutr 2002;34(5):496- 498.

Borrelli O, Salvia G, Campanozzi A, et al. Use of a new thickened formula for treatment of symptomatic gastrooesophageal reflux in infants. Ital J Gastroenterol.Hepatol. 1997;29(3):237- 242.

Carroll AE, Garrison MM, Christakis DA. A systematic review of nonpharmacological and nonsurgical therapies for gastroesophageal reflux in infants. Arch Pediatr Adolesc.Med 2002;156(2):109- 113.

Gruendel S, Garcia AL, Otto B, et al. Carob pulp preparation rich in insoluble dietary fiber and polyphenols enhances lipid oxidation and lowers postprandial acylated ghrelin in humans. J Nutr 2006;136(6):1533- 1538.

Guggenbichler JP. Adherence of enterobacteria in infantile diarrhea and its prevention. Infection 1983;11(4):239- 242.

Kwiterovich PO Jr. The role of fiber in the treatment of hypercholesterolemia in children and adolescents. Pediatrics 1995;96(5 Pt 2):1005- 1009.

Loeb H, Vandenplas Y, Wursch P, et al. Tannin- rich carob pod for the treatment of acute- onset diarrhea. J.Pediatr.Gastroenterol.Nutr. 1989;8(4):480- 485.

McPherson V, Wright ST, Bell AD. Clinical inquiries. What is the best treatment for gastroesophageal reflux and vomiting in infants? J Fam.Pract. 2005;54(4):372- 375.

Miyazawa R, Tomomasa T, Kaneko H, et al. Effect of locust bean gum in anti- regurgitant milk on the regurgitation in uncomplicated gastroesophageal reflux. J.Pediatr.Gastroenterol.Nutr. 2004;38(5):479- 483.

Puntis JW. Re: Effect of locust bean gum in anti- regurgitant milk on the regurgitation in uncomplicated gastroesophageal reflux. J Pediatr Gastroenterol.Nutr 2005;40(1):101- 102.

Savino F, Muratore MC, Silvestro L, et al. Allergy to carob gum in an infant. J.Pediatr.Gastroenterol.Nutr. 1999;29(4):475- 476.

Trommer H, Neubert RH. The examination of polysaccharides as potential antioxidative compounds for topical administration using a lipid model system. Int J Pharm 7- 14- 2005;298(1):153- 163.

Turnbull LA, Santamaria S, Martorell T, et al. Seed size variability: from carob to carats. Biology Letters 2006;2:397- 400.

Wenzl TG, Schneider S, Scheele F, et al. Effects of thickened feeding on gastroesophageal reflux in infants: a placebo- controlled crossover study using intraluminal impedance. Pediatrics 2003;111(4 Pt 1):e355- e359.

Zunft HJ, Luder W, Harde A, et al. Carob pulp preparation for treatment of hypercholesterolemia. Adv.Ther. 2001;18(5):230- 236.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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