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  • Basic Info
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Generic: ibuprofen-oxycodone
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It is used to treat moderate to severe pain for 7 days or less

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What is this medicine?

IBUPROFEN; OXYCODONE (eye BYOO proe fen; ox i KOE done) is a pain reliever. It is used to treat moderate to severe pain for 7 days or less.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • brain tumor
  • cigarette smoker
  • constipation or other intestinal problems
  • drink more than 3 alcohol containing drinks per day
  • drug abuse or addiction
  • kidney disease
  • lung or breathing disease, like asthma
  • recent head injury
  • stomach ulcers
  • an unusual or allergic reaction to oxycodone, codeine, ibuprofen, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take your medicine more often than directed.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • cidofovir
  • methotrexate
  • pemetrexed

This medicine may also interact with the following medications:

  • alcohol
  • antihistamines for allergy, cough and cold
  • aspirin and aspirin- like drugs
  • atropine
  • barbiturates, like phenobarbital
  • certain medicines for bladder problems like oxybutynin, tolterodine
  • certain medicines for stomach problems like dicyclomine, hyoscamine
  • diuretics
  • ipratropium
  • lithium
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • medicines for travel sickness like scopolamine
  • medicines that treat or prevent blood clots like warfarin
  • muscle relaxants
  • naltrexone, naloxone
  • narcotic medicines (opiates) for pain
  • other NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • some medicines for high blood pressure like enalapril
  • some medicines for Parkinson's disease like benztropine, trihexyphenidyl
  • steroid medicines like prednisone or cortisone
  • tramadol

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