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  • Basic Info
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What is this medicine?

HYDROCHLOROTHIAZIDE; METHYLDOPA (hye droe klor oh THYE a zide; meth ill DOE pa) is a combination of a diuretic and another medicine used to lower blood pressure. It is used to treat high blood pressure.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • anemia
  • diabetes
  • gout
  • immune system problems, like lupus
  • kidney disease
  • liver disease
  • small amount of urine or difficulty passing urine
  • taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in the last 14 days
  • an unusual or allergic reaction to hydrochlorothiazide, methyldopa, sulfa drugs, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

This medicine also may interact with the following medications:

  • alcohol
  • barbiturates, like phenobarbital
  • cholestyramine
  • colestipol
  • digoxin
  • diuretics
  • iron salts
  • lithium
  • medicines for anesthesia
  • medicines for blood pressure
  • medicines for diabetes
  • narcotic medicines used for pain
  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
  • medicines used to relax muscles during surgery
  • steroid medicines like prednisone or cortisone

               
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