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  • Basic Info
Licensed from
Generic: guarana
an herbal product - treats Cognitive enhancement, Mood enhancement, and Weight loss

To get info about second drug, type a name above.


This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration ( Ethan Basch, MD, MPhil (Memorial Sloan- Kettering Cancer Center); Thomas Brendler (PlantaPhile); Julie Conquer, PhD (RGB Consulting); Cynthia Dacey, PharmD (Northeastern University); Nicole Giese, MS (Natural Standard Research Collaboration); Joerg Gruenwald, PhD (Phytopharm); David S. Lee, PharmD (Massachusetts College of Pharmacy); Nikos Linardakis, MD (Natural Standard Research Collaboration); Joe Naclerio, PharmD (Massachusetts College of Pharmacy); Carolyn Williams Orlando, MA (Natural Standard Research Collaboration); Lisa Scully, PharmD (Massachusetts College of Pharmacy); Roy Soto (Natural Standard Research Collaboration); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration); Mamta Vora, PharmD (Northeastern University).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Berube- Parent S, Pelletier C, Dore J, et al. Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin- 3- gallate and caffeine on 24 h energy expenditure and fat oxidation in men. Br J Nutr 2005;94(3):432- 436.

Boutroy MJ, Vert P, Monin P, et al. Methylation of theophylline to caffeine in premature infants. Lancet 4- 14- 1979;1(8120):830.

Cheraskin E, Ringsdorf WM, Jr. Blood- glucose levels after caffeine. Lancet 9- 21- 1968;2(7569):689.

Cole P. Coffee- drinking and cancer of the lower urinary tract. Lancet 6- 26- 1971;1(7713):1335- 1337.

Debrah K, Sherwin RS, Murphy J, et al. Effect of caffeine on recognition of and physiological responses to hypoglycaemia in insulin- dependent diabetes. Lancet 1- 6- 1996;347(8993):19- 24.

Fraumeni JF Jr, Scotto J, Dunham LJ. Coffee- drinking and bladder cancer. Lancet 11- 27- 1971;2(7735):1204.

Fukumasu H, Silva TC, Avanzo JL, et al. Chemopreventive effects of Paullinia cupana Mart var. sorbilis, the guarana, on mouse hepatocarcinogenesis. Cancer Lett. 5- 7- 2005;

Haller CA. Jacob P, Benowitz NL. Short- term metabolic and hemodynamic effects of ephedra and guarana combinations. Clin Pharmacol.Ther. 2005;77(6):560- 571.

Hess AM, Sullivan DL. Potential for toxicity with use of bitter orange extract and guarana for weight loss. Ann.Pharmacother. 2005;39(3):574- 575.

Jacobson MF, Goldman AS, Syme RH. Coffee and birth defects. Lancet 6- 27- 1981;1(8235):1415- 1416.

James JE. Is habitual caffeine use a preventable cardiovascular risk factor? Lancet 1- 25- 1997;349(9047):279- 281.

Joesoef MR, Beral V, Rolfs RT, et al. Are caffeinated beverages risk factors for delayed conception? Lancet 1- 20- 1990;335(8682):136- 137.

Nyska A, Murphy E, Foley JF, et al. Acute hemorrhagic myocardial necrosis and sudden death of rats exposed to a combination of ephedrine and caffeine. Toxicol.Sci. 2005;83(2):388- 396.

Roberts AT, Jonge- Levitan L, Parker CC, et al. The effect of an herbal supplement containing black tea and caffeine on metabolic parameters in humans. Altern Med Rev 2005;10(4):321- 325.

Shapiro P. Caffeine for allergic rhinitis. Lancet 4- 3- 1982;1(8275):793.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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