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DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.


Plant- sources containing glyconutrients may cause allergy or adverse effects in some people; it is recommended to be knowledgeable before using herbal extracts or supplements.

Side Effects and Warnings

Glyconutrients are likely safe when derived from food or supplements in recommended doses. However, use cautiously in patients taking iron supplements and in patients with a history of copper deficiency or vitamin B12 deficiency.

Pregnancy and Breastfeeding

Glyconutrients are essential in cellular communication and are important for pregnant and lactating women. However, scientific evidence investigating the therapeutic use of these nutrients is currently lacking.


Interactions with Drugs

Glyconutrient commercial products that contain Vitamin K may interact with blood thinners and thus should be avoided. Similarly, glyconutrients containing ubidecarenone may diminish the response to warfarin (Coumadin®), and patients should be monitored.

Interactions with Herbs and Dietary Supplements

Glyconutritional supplements may decrease copper levels, increase iron levels or increase folic acid levels in the body. Dosing of supplements may need adjustment when taking glyconutrients.

Glyconutrient commercial products that contain Vitamin K may interact with blood thinners and thus should be avoided.


This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration ( Julie Conquer, PhD (RGB Consulting); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Axford JS, Mackenzie L, Lydyard PM, et al. Reduced B- cell galactosyltransferase activity in rheumatoid arthritis. Lancet 12- 26- 1987;2(8574):1486- 1488.

Dykman KD, Dykman RA. Effect of nutritional supplements on attentional- deficit hyperactivity disorder. Integr Physiol Behav Sci 1998;33(1):49- 60.

Dykman K, Ford CR, Gardiner T. The effect of glyconutritional supplementation on toddlers with failure to thrive. Glycoscience & Nutrition 2000;1(36):1- 7.

Flogel M, Lauc G, Gornik I, et al. Fucosylation and galactosylation of IgG heavy chains differ between acute and remission phases of juvenile chronic arthritis. Clin Chem Lab Med. 1998;36(2):99- 102.

Genius SJ, Genius SK. Use of nutraceuticals in menopause: case reports. Proc Fisher Inst Med Res 1997;1:32- 34.

Routier FH, Hounsell EF, Rudd PM, et al. Quantitation of the oligosaccharides of human serum IgG from patients with rheumatoid arthritis: a critical evaluation of different methods. J Immunol Methods 4- 15- 1998;213(2):113- 130.

Talent JM, Gracy RW. Pilot study of oral polymeric N- acetyl- D- glucosamine as a potential treatment for patients with osteoarthritis. Clin Ther 1996;18(6):1184- 1190.

Wang C, Szabo JS, Dykman RA. Effects of a carbohydrate supplement upon resting brain activity. Integr Physiol Behav Sci 2004;39(2):126- 138.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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