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  • Basic Info
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Generic: fluoxetine-olanzapine
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It is used to treat episodes of depression that have not been relieved by the use of other medicines and depression caused by bipolar disorder.
               



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What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • other medicines containing fluoxetine or olanzapine, such as Prozac, Sarafem, or Zyprexa
  • cisapride
  • dofetilide
  • dronedarone
  • linezolid
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • methylene blue (injected into a vein)
  • metoclopramide
  • pimozide
  • thioridazine
  • ziprasidone

This medicine may also interact with the following medications:

  • alcohol
  • aspirin or aspirin- like medicines
  • carbamazepine
  • certain medicines for depression, anxiety, or psychotic disturbances
  • certain medicines for migraine headaches like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
  • digoxin
  • diuretics
  • fentanyl
  • flecainide
  • furazolidone
  • isoniazid
  • lithium
  • medicines for high blood pressure
  • medicines for Parkinson's disease
  • medicines for sleep
  • medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • omeprazole
  • other medicines that prolong the QT interval (cause an abnormal heart rhythm)
  • phenytoin
  • procarbazine
  • propafenone
  • rifampin
  • ritonavir
  • supplements like St. John's wort, kava kava, valerian
  • tramadol
  • tryptophan
  • vinblastine

What should I watch for while using this medicine?

Tell your doctor if your symptoms do not get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress. Because it may take several weeks to see the full effects of this medicine, it is important to continue your treatment as prescribed by your doctor.

Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.

               
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