What may interact with this medicine?

• atazanavir
• fosamprenavir
• tipranavir

This medicine may also interact with the following medications:

• clarithromycin
• cyclosporine
• medicines for blood pressure, heart disease, irregular heart beat
• medicines for cholesterol like simvastatin
• medicines for fungal infections like ketoconazole and itraconazole
• medicines for seizures like carbamazepine, phenobarbital, phenytoin
• medicines for sleep
• methadone
• other medicines for HIV
• rifabutin
• rifampin
• rifapentine
• sirolimus
• St. John's wort
• tacrolimus
• warfarin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non- prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

What side effects may I notice from receiving this medicine?

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• dark urine
• fast, irregular heartbeat
• general ill feeling or flu- like symptoms
• light- colored stools
• loss of appetite, nausea
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• right upper belly pain
• unusually weak or tired
• yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• diarrhea
• nausea, vomiting
• dizziness
• stomach pain
• weight gain around waist, back, or thinning of face, arms, legs

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1- 800- FDA- 1088.