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  • Basic Info
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Generic: estradiol-norethindrone transdermal
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This medicine helps to relieve the symptoms of menopause like hot flashes, night sweats, mood changes, and vaginal dryness and irritation
               



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What if I miss a dose?

If you forget to change your patch as scheduled, apply it as soon as possible. Remember to remove the old patch. If it is almost time to apply the next patch, skip the missed patch and get back on your normal schedule. Do not wear more than one patch at a time unless you are told to do so by your doctor or health care professional.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone

This medicine may also interact with the following medications:

  • barbiturates, such as phenobarbital
  • benzodiazepines
  • bosentan
  • bromocriptine
  • carbamazepine
  • cimetidine
  • cyclosporine
  • dantrolene
  • grapefruit juice
  • griseofulvin
  • hydrocortisone, cortisone, or prednisolone
  • isoniazid (INH)
  • medications for diabetes
  • methotrexate
  • mineral oil
  • phenytoin
  • raloxifene
  • rifabutin, rifampin, or rifapentine
  • tamoxifen
  • thyroid hormones
  • topiramate
  • tricyclic antidepressants
  • warfarin

What should I watch for while using this medicine?

Visit your health care professional for regular checks on your progress. You should have a complete check- up every 6 months. You will need a regular breast and pelvic exam. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines.

This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.

If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.

Tobacco smoking increases the risk of getting a blood clot or having a stroke, especially if you are more than 35 years old. You are strongly advised not to smoke.

If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.

If you are going to have elective surgery, you may need to stop taking this medicine beforehand. Consult your health care professional for advice prior to scheduling the surgery.

If you are going to have a MRI procedure, let your MRI technician know about the use of these patches. Some drug patches contain an aluminized backing that can become heated when exposed to MRI and may cause burns. You may need to temporarily remove the patch during the MRI procedure.

You may bathe or participate in other activities while wearing your patch. If the patch pulls loose or falls off, you may reapply it if the patch is sticky enough to stay on the skin. You should reapply the patch in a different area. Otherwise use a fresh patch.

               
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