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  • Basic Info
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Generic: estradiol topical
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It is used for symptoms of menopause like hot flashes, night sweats, and mood changes
               



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What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone

This medicine may also interact with the following medications:

  • antibiotics used to treat tuberculosis like rifabutin, rifampin and rifapentine
  • raloxifene or tamoxifen
  • warfarin

What should I watch for while using this medicine?

Visit your health care professional for regular checks on your progress. You will need a regular breast and pelvic exam. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines.

This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.

If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.

Tobacco smoking increases the risk of getting a blood clot or having a stroke, especially if you are more than 35 years old. You are strongly advised not to smoke.

If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.

If you are going to have elective surgery, you may need to stop taking this medicine beforehand. Consult your health care professional for advice prior to scheduling the surgery.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • breakthrough bleeding and spotting
  • breast tissue changes or discharge
  • chest pain
  • confusion, forgetfulness
  • leg, arm or groin pain
  • nausea, vomiting
  • severe headaches
  • speech problems
  • stomach pain (severe)
  • sudden shortness of breath
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in emotions or mood
  • changes in sex drive or performance
  • increased or decreased appetite
  • skin rash, acne, or brown spots on the skin
  • symptoms of vaginal infection like itching, irritation or unusual discharge
  • weight gain

               
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