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  • Basic Info
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Generic: erythromycin-sulfisoxazole
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It is used to treat certain kinds of bacterial infections

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What is this medicine?

ERYTHROMYCIN, SULFISOXAZOLE (er ith roe MYE sin, sul fi SOX a zole) is combination of a macrolide and a sulfonamide antibiotic. It is used to treat certain kinds of bacterial infections. It It will not work for colds, flu, or other viral infections.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • asthma
  • glucose- 6- phosphate dehydrogenase (G6PD) deficiency
  • kidney disease
  • liver disease
  • myasthenia gravis
  • an unusual or allergic reaction to erythromycin, sulfisoxazole, sulfa drugs, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with glass of water. Follow the directions on the prescription label. Shake well before using. Use a specially marked spoon, or container to measure the medicine. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not skip doses or stop your medicine early even if you feel better. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 months of age for selected conditions, precautions do apply. Do not use in children under 2 months old.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • arsenic trioxide
  • cisapride
  • dihydroergotamine, ergotamine
  • droperidol
  • grepafloxacin
  • medicines for cholesterol like lovastatin, simvastatin
  • medicines for heart rhythm like disopyramide, dofetilide
  • mesoridazine
  • pimozide
  • ranolazine
  • red yeast rice
  • sparfloxacin
  • thioridazine
  • vinblastine
  • ziprasidone

This medicine may also interact with the following medications:

  • bromocriptine
  • carbamazepine
  • cilostazol
  • cyclosporine
  • digoxin
  • medicines for anxiety or sleep like alprazolam, triazolam
  • medicines for diabetes
  • medicines for seizures like hexobarbital and phenytoin
  • methotrexate
  • methylprednisolone
  • other antibiotics
  • quinidine
  • sildenafil, vardenafil
  • tacrolimus
  • theophylline
  • warfarin

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