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  • Basic Info
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Generic: duloxetine
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It is used to treat depression
               



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What is this medicine?

DULOXETINE (doo LOX e teen) is an antidepressant. It is used to treat depression. It is also used to treat different types of chronic pain.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bipolar disorder or a family history of bipolar disorder
  • kidney or liver disease
  • narrow- angle glaucoma
  • suicidal thoughts or a previous suicide attempt
  • taken medicines called MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate within 14 days
  • an unusual reaction to duloxetine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew this medicine. You can take this medicine with or without food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition may worsen.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • certain diet drugs like dexfenfluramine, fenfluramine
  • desvenlafaxine
  • linezolid
  • MAOIs like Azilect, Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • methylene blue (intravenous)
  • milnacipran
  • thioridazine
  • venlafaxine

This medicine may also interact with the following medications:

  • alcohol
  • aspirin and aspirin- like medicines
  • certain antibiotics like ciprofloxacin and enoxacin
  • certain medicines for blood pressure, heart disease, irregular heart beat
  • certain medicines for depression, anxiety, or psychotic disturbances
  • certain medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
  • certain medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
  • cimetidine
  • fentanyl
  • lithium
  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
  • phentermine
  • procarbazine
  • sibutramine
  • St. John's wort
  • theophylline
  • tramadol
  • tryptophan

               
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