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  • Basic Info
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Generic: drospirenone
It is used as hormone replacement in menopausal women who still have their uterus
               



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What is this medicine?

DROSPIRENONE; ESTRADIOL (dro SPY re nown; es tra DYE ole) is used as hormone replacement in menopausal women who still have their uterus. This medicine is used to treat some of the symptoms of menopause like hot flashes and vaginal dryness.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • blood vessel disease or blood clots
  • breast, cervical, endometrial, or uterine cancer
  • diabetes
  • endometriosis
  • fibroids
  • gallbladder disease
  • heart disease or recent heart attack
  • high blood cholesterol
  • high blood pressure
  • high level of calcium in the blood
  • hysterectomy
  • kidney disease
  • liver disease
  • mental depression
  • migraine headaches
  • porphyria
  • stroke
  • systemic lupus erythematosus (SLE)
  • tobacco smoker
  • vaginal bleeding
  • an unusual or allergic reaction to estrogens, progestins, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine at the same time each day. Do not take your medicine more often than directed.

A patient package insert for the product will be given with each prescription and refill. Read this sheet carefully each time. The sheet may change frequently.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone, vorozole

This medicine may also interact with the following medications:

  • antibiotics like clarithromycin, erythromycin
  • carbamazepine
  • female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
  • grapefruit juice
  • griseofulvin
  • itraconazole
  • ketoconazole
  • medicines that treat or prevent blood clots like warfarin
  • other medicines or supplements for menopause or female problems
  • phenobarbital
  • rifampin
  • ritonavir
  • St. John's Wort

               
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