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  • Basic Info
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Generic: diphenhydrAMINE-ibuprofen
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It is used to treat occasional sleeplessness with minor aches and pains
               



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What is this medicine?

DIPHENHYDRAMINE; IBUPROFEN (dye fen HYE dra meen; eye BYOO proe fen) is a combination of a sleep- aid and a non- steroidal anti- inflammatory drug (NSAID). It is used to treat occasional sleeplessness with minor aches and pains.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • asthma
  • drink more than 3 alcohol containing drinks a day
  • glaucoma
  • heart disease
  • high blood pressure
  • kidney disease
  • liver disease
  • not drinking fluids
  • pain or difficulty passing urine
  • prostate trouble
  • sore throat with high fever, headache, nausea or vomiting
  • stomach bleeding or ulcers
  • an unusual or allergic reaction to ibuprofen, aspirin, other NSAIDs, diphenhydramine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food if your stomach gets upset. Try to not lie down for at least 10 minutes after you take the medicine. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.

Patients over 60 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • cidofovir
  • ketorolac
  • methotrexate
  • pemetrexed

This medicine may also interact with the following medications:

  • alcohol
  • alendronate
  • aspirin and aspirin- like medicines
  • celecoxib
  • flavocoxid
  • ginkgo
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for cold, cough or allergy
  • medicines for sleep
  • other NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
  • steroid medicines like prednisone or cortisone
  • warfarin

               
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