Generic: copper sulfate
a minerals and electrolyte - treats Age-related macular degeneration, Menkes' kinky-hair disease, Alzheimer's disease prevention, Cardiovascular disease prevention / atherosclerosis, Dental conditions, Metabolic disorders, Immune system function, Marasmus, Neural-tube defect prevention, Osteoporosis / osteopenia, Copper deficiency, Cancer, Schizophrenia, Arthritis, Sideroblastic anemia, Plaque prevention, Systemic lupus erythematosus, and Childhood growth promotion
This information is based on a professional level monograph edited and peer- reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Ethan Basch, MD, MSc, MPhil (Memorial Sloan- Kettering Cancer Center); Julie Conquer, PhD (RGB Consulting); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Tamara Milkin, PharmD (Northeastern University); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Christine Ulbricht, BS (University of Massachusetts); Wendy Weissner, BA (Natural Standard Research Collaboration); Jen Woods, BS (Natural Standard Research Collaboration).
BibliographyDISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Abdullah AZ, Strafford SM, Brookes SJ, et al. The effect of copper on demineralization of dental enamel. J Dent Res 2006 Nov;85(11):1011- 5.
Araya M, Olivares M, Pizarro F, et al. Community- based randomized double- blind study of gastrointestinal effects and copper exposure in drinking water. Environ Health Perspect 2004;112(10):1068- 1073.
Behera C, Rautji R, Dogra TD. An unusual suicide with parenteral copper sulphate poisoning: a case report. Med Sci Law 2007 Oct;47(4):357- 8.
Bonham M, O'Connor JM, McAnena LB, et al. Zinc supplementation has no effect on lipoprotein metabolism, hemostasis, and putative indices of copper status in healthy men. Biol Trace Elem Res 2003;93(1- 3):75- 86.
Bremner I. Manifestations of copper excess. Am J Clin Nutr 1998;67(5 Suppl):1069S- 1073S.
Donoso A, Cruces P, Camacho J, et al. Acute respiratory distress syndrome resulting from inhalation of powdered copper. Clin Toxicol (Phila) 2007 Sep;45(6):714- 6.
el Kholy MS, Gas Allah MA, el Shimi S, et al. Zinc and copper status in children with bronchial asthma and atopic dermatitis. J Egypt Public Health Assoc 1990;65(5- 6):657- 668.
Ferretti G, Bacchetti T, Menanno F, et al. Effect of genistein against copper- induced lipid peroxidation of human high density lipoproteins (HDL). Atherosclerosis 2004;172(1):55- 61.
Gunay N, Yildirim C, Karcioglu O, et al. A series of patients in the emergency department diagnosed with copper poisoning: recognition equals treatment. Tohoku J Exp Med 2006 Jul;209(3):243- 8.
Jones AA, DiSilvestro RA, Coleman M, et al. Copper supplementation of adult men: effects on blood copper enzyme activities and indicators of cardiovascular disease risk. Metabolism 1997;46(12):1380- 1383.
Klevay LM. Dietary copper and risk of coronary heart disease. Am J Clin Nutr 2000;71(5):1213- 1214.
Mellacheruvu S, Vergara C. A 32- year- old patient with hemolytic anemia and fulminant hepatic failure. Conn Med 2006 May;70(5):293- 5.
Oon S, Yap CH, Ihle BU. Acute copper toxicity following copper glycinate injection. Intern Med J 2006 Nov;36(11):741- 3.
Patterson RA, Lamb DJ, Leake DS. Mechanisms by which cysteine can inhibit or promote the oxidation of low density lipoprotein by copper. Atherosclerosis 2003;169(1):87- 94.
Rock E, Mazur A, O'Connor JM, et al. The effect of copper supplementation on red blood cell oxidizability and plasma antioxidants in middle- aged healthy volunteers. Free Radic Biol Med 2000;28(3):324- 329.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.