What if I miss a dose?

What may interact with this medicine?

• alcohol
• certain medicines for coughs and colds
• certain medicines to help you breathe better
• cyclosporine
• epinephrine
• grapefruit or grapefruit juice
• methenamine
• sodium bicarbonate
• some antibiotics
• some medicines for an irregular heartbeat or other heart problems
• some medicines for cancer, like lapatinib and tamoxifen
• some medicines for fungal infection
• some medicines for HIV

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non- prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

What side effects may I notice from receiving this medicine?

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• fever, chills, or sore throat
• muscle tenderness, pain, or weakness
• numbness or tingling in hands or feet
• unusual bleeding or bruising
• unusually weak or tired
• vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• diarrhea
• hair loss
• loss of appetite
• stomach pain or nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1- 800- FDA- 1088.