a vitamin - treats Osteogenesis imperfecta, Proximal myopathy, Fall prevention, Colorectal cancer, Skin pigmentation disorders, Vitamin D deficiency, Hepatic osteodystrophy, Muscle weakness/pain, Immunomodulation, Muscle strength, Fanconi syndrome-related hypophosphatemia, Mortality reduction, Psoriasis, Hypocalcemia due to hypoparathyroidism, Cancer prevention, Breast cancer prevention, Senile warts, Tooth retention, Corticosteroid-induced osteoporosis, Anticonvulsant-induced osteomalacia, Hypertriglyceridemia, Multiple sclerosis, High blood pressure, Osteoporosis, Diabetes, Seasonal affective disorder, Myelodysplastic syndrome, Prostate cancer, Familial hypophosphatemia, Rickets, Renal osteodystrophy, Weight gain, Hyperparathyroidism due to low vitamin D levels, and Osteomalacia
This information is based on a systematic review of scientific literature, and has been edited and peer- reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Ethan Basch, MD, MSc, MPhil (Memorial Sloan Kettering Cancer Center); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Cynthia Dacey, PharmD (University of Rhode Island); Dana A. Hackman, BS (Northeastern University); Jenna Hollenstein, MS, RD (Natural Standard Research Collaboration); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Christine Ulbricht, PharmD (University of Massachusetts); Wendy Weissner, BA (Natural Standard Research Collaboration).
BibliographyDISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
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Deane A, Constancio L, Fogelman I, et al. The impact of vitamin D status on changes in bone mineral density during treatment with bisphosphonates and after discontinuation following long- term use in post- menopausal osteoporosis. BMC Musculoskelet Disord 2007 Jan 10;8:3.
Goldstein MR. Myopathy, statins, and vitamin D deficiency. Am J Cardiol. 2007 Oct 15;100(8):1328. Epub 2007 Jun 29. Comment on: Am J Cardiol 2007 Apr 15;99(8):1171- 6.
Gorham ED, Garland CF, Garland FC, et al. Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis Am J Prev Med 2007 Mar;32(3):210- 6.
Helfrich YR, Kang S, Hamilton TA, et al. Topical becocalcidiol for the treatment of psoriasis vulgaris: a randomized, placebo- controlled, double- blind, multicentre study. Br J Dermatol 2007 Aug;157(2):369- 74.
Izaks GJ. Fracture prevention with vitamin D supplementation: considering the inconsistent results. BMC Musculoskelet Disord 2007 Mar 9;8:26.
Lappe JM, Travers- Gustafson D, Davies KM, et al. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr 2007 Jun;85(6):1586- 91.
Lind L, Wengle B, Wide L, et al. Reduction of blood pressure during long- term treatment with active vitamin D (alphacalcidol) is dependent on plasma renin activity and calcium status. A double- blind, placebo- controlled study. Am J Hypertens 1989;2(1):20- 25.
Lyons RA, Johansen A, Brophy S, et al. Preventing fractures among older people living in institutional care: a pragmatic randomised double blind placebo controlled trial of vitamin D supplementation. Osteoporos Int 2007 Jun;18(6):811- 8.
Pittas AG, Lau J, Hu FB, et al. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta- analysis. J Clin Endocrinol Metab 2007 Jun;92(6):2017- 29.
Robien K, Cutler GJ, Lazovich D. Vitamin D intake and breast cancer risk in postmenopausal women: the Iowa Women's Health Study. Cancer Causes Control 2007 Sep;18(7):775- 82.
Schumann SA, Ewigman B. Double- dose vitamin D lowers cancer risk in women over 55. J Fam Pract 2007 Nov;56(11):907- 10.
Tau C, Ciriani V, Scaiola E, et al. Twice single doses of 100,000 IU of vitamin D in winter is adequate and safe for prevention of vitamin D deficiency in healthy children from Ushuaia, Tierra Del Fuego, Argentina. J Steroid Biochem Mol Biol 2007 Mar;103(3- 5):651- 4.
Wactawski- Wende J, Kotchen JM, Anderson GL, et al. Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med 2006 Feb 16;354(7):684- 96.
Wagner CL, Greer FR, Section on Breastfeeding and Committee on Nutrition. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics 2008; 122(5): 1142- 1152.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.