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  • Basic Info
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Generic: ergocalciferol
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a vitamin - treats Osteogenesis imperfecta, Proximal myopathy, Fall prevention, Colorectal cancer, Skin pigmentation disorders, Vitamin D deficiency, Hepatic osteodystrophy, Muscle weakness/pain, Immunomodulation, Muscle strength, Fanconi syndrome-related hypophosphatemia, Mortality reduction, Psoriasis, Hypocalcemia due to hypoparathyroidism, Cancer prevention, Breast cancer prevention, Senile warts, Tooth retention, Corticosteroid-induced osteoporosis, Anticonvulsant-induced osteomalacia, Hypertriglyceridemia, Multiple sclerosis, High blood pressure, Osteoporosis, Diabetes, Seasonal affective disorder, Myelodysplastic syndrome, Prostate cancer, Familial hypophosphatemia, Rickets, Renal osteodystrophy, Weight gain, Hyperparathyroidism due to low vitamin D levels, and Osteomalacia
               



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Alternate Title

Alternate Title

Calcitriol

Category

Herbs & Supplements

Synonyms

1 alpha (OH) D3, 19- nor- 1, 1 alpha- hydroxyvitamin D2, 1,25- DHCC, 1,25- dihydroxy- 22- ovavitamin D(3), 1,25- dihydroxycholecalciferol, 1,25- dihydroxyvitamin D3, 1,25- diOHC, 1,25(0H) 2D3, 1- alpha- hydroxycholecalciferol, 22- oxacalcitriol (OCT), 25- dihydroxyvitamin D2, 25- dihydroxyvitamin D2, 19- nor- 1, 25- HCC, 25- hydroxycholecalciferol, 25- hydroxyvitamin D3, 25- OHCC, 25- OHD3, activated 7- dehydrocholesterol, activated ergosterol, alfacalcidol, calcifediol, calcipotriene, calcipotriol, calcitriol, cholecalciferol, colecalciferol, dichysterol, dihydrotachysterol 2, dihydrotachysterol, ecocalcidiol, ED- 21 (vitamin D analog), ED- 71 (vitamin D analog), ergocalciferol, ergocalciferolum, hexafluoro- 1,25dihydroxyvitamin D3, irradiated ergosterol, MC903, paracalcin, paricalcitol, viosterol, vitamin D2, vitamin D3.

Background

Vitamin D is found in many dietary sources such as fish, eggs, fortified milk, and cod liver oil. The sun also contributes significantly to the daily production of vitamin D, and as little as 10 minutes of exposure is thought to be enough to prevent deficiencies. The term "vitamin D" refers to several different forms of this vitamin. Two forms are important in humans: ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Vitamin D2 is synthesized by plants. Vitamin D3 is synthesized by humans in the skin when it is exposed to ultraviolet- B (UVB) rays from sunlight. Foods may be fortified with vitamin D2 or D3.

The major biologic function of vitamin D is to maintain normal blood levels of calcium and phosphorus. Vitamin D aids in the absorption of calcium, helping to form and maintain strong bones. Recently, research also suggests vitamin D may provide protection from osteoporosis, hypertension (high blood pressure), cancer, and several autoimmune diseases.

Rickets and osteomalacia are classic vitamin D deficiency diseases. In children, vitamin D deficiency causes rickets, which results in skeletal deformities. In adults, vitamin D deficiency can lead to osteomalacia, which results in muscular weakness in addition to weak bones. Populations who may be at a high risk for vitamin D deficiencies include the elderly, obese individuals, exclusively breastfed infants, and those who have limited sun exposure. Also, individuals who have fat malabsorption syndromes (e.g., cystic fibrosis) or inflammatory bowel disease (e.g., Crohn's disease) are at risk.

               
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