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  • Basic Info
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Generic: chlorophyllin
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an uncategorized agent - treats Herpes, Rheumatoid arthritis, Protection from aflatoxins, Poisoning, Tuberculosis, Reduction of odor from incontinence/bladder catheterization, Fibrocystic breast disease, Cancer, Pancreatitis, and Pneumonia

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This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration ( Rebecca Bramwell, PharmD (Northeastern University); Thuy- Duong Le, PharmD (Oregon State University); Nicole Giese, MS (Natural Standard Research Collaboration); Julie Montalbano, PharmD (Massachusetts College of Pharmacy); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Nicole J. Trelour, ND (Symbion Health, Australia); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration); Heeja Yoon, PharmD (Drake University); Mario M. Zeolla, PharmD, BCPS (Albany College of Pharmacy).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Abbott BL. ABCG2 (BCRP) expression in normal and malignant hematopoietic cells. Hematol Oncol 2003;21(3):115- 130.

Acheson DW, Flegg PJ. Diagnostic delay due to chlorophyll in oral rehydration solution. Lancet 1- 17- 1987;1(8525):171.

Adida A, Spener F. Intracellular lipid binding proteins and nuclear receptors involved in branched- chain fatty acid signaling. Prostaglandins Leukot Essent Fatty Acids 2002;67(2- 3):91- 98.

Bezpalov VG, Barash NI, Ivanova OA, et al. [Investigation of the drug "Mamoclam" for the treatment of patients with fibroadenomatosis of the breast]. Vopr Onkol 2005;51(2):236- 241.

Egner PA, Munoz A, Kensler TW. Chemoprevention with chlorophyllin in individuals exposed to dietary aflatoxin. Mutat.Res 2003;523- 524:209- 216.

Fahey JW, Stephenson KK, Dinkova- Kostova AT, et al. Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes. Carcinogenesis 2005;26(7):1247- 1255.

Lim DS, Ko SH, Kim SJ, et al. Photoinactivation of vesicular stomatitis virus by a photodynamic agent, chlorophyll derivatives from silkworm excreta. J Photochem Photobiol B 2002;67(3):149- 156.

Lozovskaia ME. [Effectiveness of using the biologically active additive to food from Laminaria in adolescents during complex treatment of the pulmonary tuberculosis]. Vopr Pitan 2005;74(1):40- 43.

Mukherji M, Schofield CJ, Wierzbicki AS, et al. The chemical biology of branched- chain lipid metabolism. Prog Lipid Res 2003;42(5):359- 376.

Nagayama J, Takasuga T, Tsuji H, et al. Promotive excretion of causative agents of Yusho by one year intake of FBRA in Japanese people. Fukuoka Igaku Zasshi 2005;96(5):241- 248.

Nagayama J, Takasuga T, Tsuji H, et al. Active elimination of causative PCDFs/ DDs congeners of Yusho by one year intake of FBRA in Japanese people. Fukuoka Igaku Zasshi 2003;94(5):118- 125.

Schluter A, Yubero P, Iglesias R, et al. The chlorophyll- derived metabolite phytanic acid induces white adipocyte differentiation. Int J Obes Relat Metab Disord 2002;26(9):1277- 1280.

Sugiyama C, Nakandakari N, Hayatsu H, et al. Preventive effects of chlorophyllin fixed on chitosan towards DNA adduct formation of 3- amino- 1- methyl- 5H- pyrido [4,3- b]indole in CDF1 mice. Biol Pharm Bull 2002;25(4):520- 522.

Tajmir- Riahi HA, Neault JF, Diamantoglou S. DNA adducts with chlorophyll and chlorophyllin as antimutagenic agents: synthesis, stability, and structural features. Methods Mol Biol 2004;274:159- 171.

Tsukagoshi S. [Development of a novel photosensitizer, talaporfin sodium, for the photodynamic therapy (PDT)]. Gan To Kagaku Ryoho 2004;31(6):979- 985.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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