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  • Basic Info
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Generic: caffeine-ergotamine
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It is used to treat or prevent migraine and cluster headaches
               



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What is this medicine?

CAFFEINE; ERGOTAMINE (KAF een; er GOT a meen) is part of a group of medicines called ergot alkaloids. It is used to treat or prevent migraine and cluster headaches.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • heart or blood vessel disease
  • high blood pressure
  • infection
  • kidney disease
  • liver disease
  • poor circulation
  • an unusual or allergic reaction to caffeine, ergotamine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not stop taking except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply. You should only take this medicine at the first sign of an attack. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • antifungal drugs like fluconazole, itraconazole, ketoconazole or voriconazole
  • certain antibiotics like erythromycin, clarithromycin, and troleandomycin
  • cocaine
  • conivaptan
  • dexfenfluramine
  • ephedrine
  • feverfew
  • grapefruit juice
  • imatinib
  • isoproterenol
  • medicines called nitrates like isosorbide and nitroglycerin
  • medicines for colds, flu, or breathing difficulties like phenylephrine and pseudoephedrine
  • medicines for HIV or AIDS called protease inhibitors, delavirdine, efavirenz, nelfinavir
  • medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, and zolmitriptan
  • midodrine
  • nefazodone
  • other ergot alkaloids like bromocriptine, cabergoline, dihydroergotamine, ergoloid mesylates, ergonovine, methylergonovine, and methysergide

This medicine may also interact with the following medications:

  • clotrimazole
  • fluoxetine
  • fluvoxamine
  • medicines for high blood pressure, especially beta- blockers
  • metronidazole
  • nicotine
  • zileuton

What should I watch for while using this medicine?

Check with your doctor or health care professional if you do not get relief from your headaches after using this medicine. You may need to be changed to a different kind of medicine to treat your migraines.

This medicine decreases the circulation of blood to your skin, fingers, and toes. You may get more sensitive to the cold. Elderly patients are more likely to feel this effect. Dress warmly and avoid long exposure to the cold.

This medicine contains caffeine. Limit your intake of caffeinated beverages on the days that you use this medicine.

               
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