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  • Basic Info
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Generic: belladonna/ergotamine/phenobarbital
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It is used to help prevent headaches when it is taken on a regular basis

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What is this medicine?

BELLADONNA ALKALOIDS; ERGOTAMINE; PHENOBARBITAL (bell a DON a; er GOT a meen; fee noe BAR bi tal) is a combination of several different drugs. It is used to help prevent headaches when it is taken on a regular basis. The medicine will not treat a headache. This drug may also be used to treat menopause symptoms.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • blood clots
  • chest pain
  • gallbladder problems
  • glaucoma
  • heart disease
  • high blood pressure
  • high cholesterol
  • infection
  • kidney disease
  • liver disease
  • myasthenia gravis
  • peripheral vascular disease
  • poor circulation
  • porphyria
  • prostate trouble
  • stomach problems
  • an unusual or allergic reaction to belladonna, ergotamine, phenobarbital, other medicines, lactose, tartrazine dye, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Do not crush, chew, or cut the tablets. If this medicine upsets your stomach, you may take it with food but not with grapefruit or grapefruit juice. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • antibiotics like erythromycin, clarithromycin, and troleandomycin
  • conivaptan
  • delavirdine
  • dopamine
  • efavirenz
  • ergot alkaloids
  • feverfew
  • imatinib
  • isoproterenol
  • medicines for fungal infections like itraconazole, voriconazole, posaconazole, and ketoconazole
  • medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
  • midodrine
  • nefazodone
  • nitrates
  • primidone
  • protease inhibitors
  • stimulant type medicines

This medicine may also interact with the following medications:

  • alcohol
  • beta blockers
  • doxycycline
  • female hormones, like estrogens or progestins and birth control pills
  • griseofulvin
  • medicines that treat or prevent blood clots like warfarin
  • pain medications
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • phenytoin
  • quinidine
  • tricyclic antidepressants
  • valproate

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