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  • Basic Info
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Generic: aloe vera
an herbal product - treats Radiation dermatitis, Genital herpes, Mucositis, Skin ulcers, Ulcerative colitis, Wound healing, HIV infection, Diabetes, Skin burns, Psoriasis vulgaris, Seborrheic dermatitis, Pressure ulcers, Cancer prevention, Constipation, Lichen planus, Canker sores, and Dry skin

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This information is based on a systematic review of scientific literature edited and peer- reviewed by contributors to the Natural Standard Research Collaboration ( Jennifer Armstrong, PharmD (University of Rhode Island); Ethan Basch, MD (Memorial Sloan- Kettering Cancer Center); Samuel Basch, MD (Mt. Sinai Medical Center, NY); Steve Bent, MD (University of California, San Francisco); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Cynthia Dacey, PharmD (Northeastern University); Sean Dalton, MD, PhD, MPH (Harvard University); Ivo Foppa, MD, ScD (Harvard University); Paul Hammerness, MD (Harvard Medical School); Jenna Hollenstein, MS, RD (Natural Standard Research Collaboration); Catherine Kirkwood, MPH, CCCJS- MAC (MD Anderson Cancer Center, University of Texas); David Sollars, M.Ac, H.M.C. (New England School of Acupuncture); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Dal'Belo SE, Gaspar LR, Maia Campos PM. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Res Technol. 2006;12(4):241- 6.

Ernst E, Pittler MH, Stevinson C. Complementary/ alternative medicine in dermatology: evidence- assessed efficacy of two diseases and two treatments. Am.J.Clin.Dermatol. 2002;3(5):341- 348.

Heggie S, Bryant GP, Tripcony L, et al. Phase III study on the efficacy of topical aloe vera gel on irradiated breast tissue. Cancer Nurs 2002;25(6):442- 451.

Kim EJ, Kim HJ, Kim SG, et al. Aloe- induced Henoch- Schonlein purpura. Nephrology (Carlton). 2007;12(1):109.

Langmead L, Feakins RM, Goldthorpe S, et al. Randomized, double- blind, placebo- controlled trial of oral aloe vera gel for active ulcerative colitis. Aliment.Pharmacol.Ther. 4- 1- 2004;19(7):739- 747.

Lee A, Chui PT, Aun CS, et al. Possible interaction between sevoflurane and Aloe vera. Ann Pharmacother. 2004;38(10):1651- 1654.

Montaner JS, Gill J, Singer J, et al. Double- blind placebo- controlled pilot trial of acemannan in advanced human immunodeficiency virus disease. J Acquir Immune Defic Syn Hum Retrovirol 1996;12:153- 157.

Natural Standard Research Collaboration, Chief Editors: Ulbricht C, Basch E, Natural Standard Herb and Supplement Reference - Evidence- Based Clinical Reviews, USA: Elsevier/ Mosby, 2005.

Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol. 1- 14- 2005;11(2):303- 304.

Schmidt JM, Greenspoon JS. Aloe vera dermal wound gel is associated with a delay in wound healing. Obstetrics & Gynecology 1991;78(1):115- 117.

Su CK, Mehta V, Ravikumar L, et al. Phase II double- blind randomized study comparing oral aloe vera versus placebo to prevent radiation- related mucositis in patients with head- and- neck neoplasms. Int.J Radiat.Oncol.Biol.Phys. 9- 1- 2004;60(1):171- 177.

Syed TA, Cheema KM, Ahmad SA, et al. Aloe vera extract 0.5% in hydrophilic cream versus aloe vera gel for the measurement of genital herpes in males. A placebo- controlled, double- blind, comparative study. Journal of the European Academy of Dermatology & Venerology 1996;7(3):294- 295.

Syed TA, Afzal M, Ashfaq AS. Management of genital herpes in men with 0.5% Aloe vera extract in a hydrophilic cream. A placebo- controlled double- blind study. J Derm Treatment 1997;8(2):99- 102.

Vardy AD, Cohen AD, Tchetov T. A double- blind, placebo- controlled trial of Aloe vera (A. barbadensis) emulsion in the treatment of seborrheic dermatitis. J Derm Treatment 1999;10(1):7- 11.

Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br.J Gen.Pract. 1999;49(447):823- 828.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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