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  • Basic Info
Licensed from
Generic: Veratrum viride
treats Cardiovascular and renal dysfunction, Pre-eclampsia/pregnancy-induced hypertension, and Hypertension
               



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Interactions

Interactions with Drugs

The use of American hellebore or its alkaloidal constituents could cause bradycardia (slowed heart rate) and combination with anti- arrhythmic drugs may be unsafe. Caution is advised.

American hellebore or its alkaloidal constituents may lower blood pressure. Patients taking medications that lower blood pressure (antihypertensives) should consult with a qualified healthcare professional, including a pharmacist.

American hellebore or its alkaloidal constituents may cause a decrease in glomerular filtration rate (GFR) and effective renal blood flow. Thus, American hellebore may interact with certain medications that increase urine flow (diuretics) such as chlorothiazide (Diuril®). Preparations of American hellebore may also interact with drugs that are excreted through the kidneys or that are potentially toxic to the kidneys.

Isolated constituents found in American hellebore may have beta- agonist and/ or beta- adrenergic blocking activity. Caution is advised in patients with cardiovascular disease or those taking beta- agonist or beta- blocker drugs.

Interactions with Herbs and Dietary Supplements

The use of American hellebore or its alkaloidal constituents could cause bradycardia (slowed heart rate) and combination with anti- arrhythmic herbs and supplements may be unsafe. Caution is advised.

American hellebore or its alkaloidal constituents may lower blood pressure. Patients taking herbs and supplements that lower blood pressure (antihypertensives) should consult with a qualified healthcare professional, including a pharmacist.

American hellebore or its alkaloidal constituents may cause a decrease in glomerular filtration rate (GFR) and effective renal blood flow. Thus, American hellebore may interact with certain herbs and supplements that increase urine flow (diuretics). Preparations may also interact with herbs and supplements that are excreted through the kidneys or that are potentially toxic to the kidneys.

Attribution

This information is based on a professional level monograph edited and peer- reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Ernest B. Hawkins, MS, BSPharm (Health Education Resources, Inc.); Nicole Giese, MS (Natural Standard Research Collaboration); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration).

               
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