Generic: Perilla frutescens
treats Asthma, Allergies, and Aphthous stomatitis
SafetyDISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.
Avoid in individuals with a known allergy or hypersensitivity to perilla. Occupational allergic contact dermatitis from Perilla frutescens has been documented.
Side Effects and Warnings
Perilla used in recommended doses is considered to be safe and well tolerated. In one study, patients reported no adverse events and no significant abnormalities were detected in routine blood tests. However, occupational allergic contact dermatitis from Perilla frutescens has been documented.
Use commercial perilla oil cautiously in patients with cancer, due to a mutagen formed in the oil, from omega- 3 fatty acids.
Pregnancy and Breastfeeding
Interactions with Drugs
Although not well studied in humans, perilla may lower HDL- cholesterol levels. Caution is advised in patients with high cholesterol or those taking any cholesterol- lowering agents.
Theoretically, perilla may suppress indomethacin- induced effects, due to a change in fatty acid and eicosanoid status. Caution is advised in patients taking indomethacin or other non- steroidal anti- inflammatory drugs (NSAIDS).
Interactions with Herbs and Dietary Supplements
Perilla frutescens may contain sedative constituents, and may interact with other herbs that have sedative properties. Drowsiness or sedation may occur. Use caution if driving or operating heavy machinery.
Theoretically, the results from an animal study suggest that the combination of perilla and beta- carotene may reduce the risk of colon cancer.
Theoretically, perilla may lower HDL- cholesterol levels. Caution is advised in patients with high cholesterol or those taking any cholesterol- lowering agents, such as red yeast rice.
Theoretically, use of fish oil or omega- 3 fatty acid sources (flax oil, walnut oil, soybean oil) and perilla oil would increase omega- 3 fatty acid status of blood and tissues to a greater effect than either alone. Caution is advised.