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  • Basic Info
Licensed from
Generic: Pc-Spes
treats Prostate cancer

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This information is based on a systematic review of scientific literature, and has been edited and peer- reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Dawn Costa, BA, BS (Natural Standard Research Collaboration); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

de la TA, Buttyan R, Hayek O, et al. Herbal therapy PC- SPES: in vitro effects and evaluation of its efficacy in 69 patients with prostate cancer. J Urol 2000;164(4):1229- 1234.

DiPaola RS, Zhang H, Lambert GH, et al. Clinical and biologic activity of an estrogenic herbal combination (PC- SPES) in prostate cancer. N Engl J Med 1998;339(12):785- 791.

Oh WK, George DJ, Hackmann K, et al. Activity of the herbal combination, PC- SPES, in the treatment of patients with androgen- independent prostate cancer. Urology 2001;57(1):122- 126.

Oh WK, Kantoff PW, Weinberg V, et al. Prospective, multicenter, randomized phase II trial of the herbal supplement, PC- SPES, and diethylstilbestrol in patients with androgen- independent prostate cancer. J Clin Oncol 2004;22(18):3705- 3712.

Pfeifer BL, Pirani JF, Hamann SR, et al. PC- SPES, a dietary supplement for the treatment of hormone- refractory prostate cancer. BJU Int 2000;85(4):481- 485.

Small EJ, Frohlich MW, Bok R, et al. Prospective trial of the herbal supplement PC- SPES in patients with progressive prostate cancer. J Clin Oncol 2000;18(21):3595- 3603.

Sovak M, Seligson AL, Konas M, et al. Herbal composition PC- SPES for management of prostate cancer: identification of active principles. J Natl Cancer Inst 2002;94(17):1275- 1281.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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