treats Hepatitis, Arthritis, Respiratory disease, HIV, Immunomodulation, and Cancer
Interactions with Drugs
Mistletoe may increase the effects of blood pressure- lowering medications or have other more serious adverse effects on the heart. Busulphan and mistletoe extract (Helixor®) have been reported to cause organ fibrosis and death.
Use of mistletoe with CNS depressants may increase sedative effects.
Elevations of liver enzymes have been reported with high doses of mistletoe. Seizure risk may be increased. Seizures have been reported to poison- control centers following the ingestion of crude mistletoe plant material. Immunomodulatory effects have also been proposed.
Theoretically, concomitant use of mistletoe and MAOIs may cause a hypertensive crisis due to mistletoe containing tyramine. Blood sugar levels may be altered by mistletoe. Mistletoe may have negative side effects on the eye and interact with eye drops.
Avoid the use of mistletoe in patients with over- active thyroid glands (a condition called hyperthyroidism). Mistletoe may cause an inflammatory reaction when used in patients with untreated hyperthyroidism.
Interactions with Herbs and Dietary Supplements
European mistletoe can have cardiotoxic and negative effects on heart beat strength, cause reflex bradycardia (slow heart rate), and depolarize cardiac muscle. Severe dehydration caused by mistletoe may lead to hypovolemic shock and cardiovascular collapse. Use cautiously with herbs or supplements that alter heart rhythm.
Use of mistletoe with CNS depressants may enhance sedative effects.
Use of mistletoe with cholinergic herbs or supplements may cause increased myosis due to additive adverse effects.
Immunomodulatory effects have been proposed.
Elevations of liver enzymes have been reported with high doses of mistletoe.
Theoretically, the concomitant use of mistletoe and MAOIs may cause a hypertensive crisis due to mistletoe containing tyramine.
It is unclear if mistletoe interacts with herbs or supplements that affect blood sugar levels or agents used to treat diabetes. Avoid the use of mistletoe in hyperthyroid patients. The manufacturer of Iscador® noted mistletoe may cause an inflammatory reaction when used during untreated hyperthyroidism.