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  • Basic Info
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Generic: methotrexate
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This medicine affects cells that are rapidly growing, such as cancer cells and cells in your mouth and stomach
               



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What is this medicine?

METHOTREXATE (METH oh TREX ate) is a chemotherapy drug. This medicine affects cells that are rapidly growing, such as cancer cells and cells in your mouth and stomach. It is used to treat many cancers and other medical conditions. It is used for leukemias, lymphomas, breast cancer, lung cancer, head and neck cancers, and other cancers. This medicine also works on the immune system and is commonly used to treat psoriasis and rheumatoid arthritis. If used for arthritis or psoriasis, the drug is only given once a week.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bleeding or blood disorders
  • HIV- positive or have acquired immunodeficiency syndrome (AIDS)
  • if you frequently drink alcohol- containing drinks
  • infection or weak immune system
  • kidney disease
  • liver disease
  • lung disease
  • stomach ulcers
  • ulcerative colitis
  • an unusual or allergic reaction to methotrexate, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth. Swallow it with a full glass of water. Follow the directions on the prescription label. Do not take your medicine more often than directed. Finish the full course prescribed by your doctor or health care professional. Do not stop taking except on your doctor's advice.

If you take methotrexate for rheumatoid arthritis or psoriasis, the dose is given only once a week. Do not take more frequently.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, talk with your doctor or health care professional. Do not take double or extra doses. If you vomit after taking a dose, call your doctor or health care professional for advice.

               
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