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  • Basic Info
Licensed from
Generic: Maitake mushroom extract.
treats Immune enhancement, Cancer, and Diabetes

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DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Fullerton SA, Samadi AA, Tortorelis DG, et al. Induction of apoptosis in human prostatic cancer cells with beta- glucan (Maitake mushroom polysaccharide). Mol Urol 2000;4(1):7- 13.

Cui FJ, Li Y, Xu YY, et al. Induction of apoptosis in SGC- 7901 cells by polysaccharide- peptide GFPS1b from the cultured mycelia of Grifola frondosa GF9801. Toxicol In Vitro 2007 Apr;21(3):417- 27.

Cui FJ, Tao WY, Xu ZH, et al. Structural analysis of anti- tumor heteropolysaccharide GFPS1b from the cultured mycelia of Grifola frondosa GF9801. Bioresour Technol 2007 Jan;98(2):395- 401.

Gu CQ, Li J, Chao FH. Inhibition of hepatitis B virus by D- fraction from Grifola frondosa: synergistic effect of combination with interferon- alpha in HepG2 2.2.15. Antiviral Res 2006 Nov;72(2):162- 5.

Gu CQ, Li JW, Chao F, et al. Isolation, identification and function of a novel anti- HSV- 1 protein from Grifola frondosa. Antiviral Res 2007 Sep;75(3):250- 7.

Hong L, Xun M, Wutong W. Anti- diabetic effect of an alpha- glucan from fruit body of maitake (Grifola frondosa) on KK- Ay mice. J Pharm Pharmacol 2007 Apr;59(4):575- 82.

Kodama N, Komuta K, Nanba H. Effect of Maitake (Grifola frondosa) D- Fraction on the activation of NK cells in cancer patients. J Med Food 2003;6(4):371- 377.

Konno S. Potential growth inhibitory effect of maitake D- fraction on canine cancer cells. Vet Ther 2004;5(4):263- 271.

Kubo K, Nanba H. Anti- hyperliposis effect of maitake fruit body (Grifola frondosa). I. Biol Pharm Bull 1997;20(7):781- 785.

Li X, Rong J, Wu M, et al. [Anti- tumor effect of polysaccharide from Grifola frondosa and its influence on immunological function]. Zhong Yao Cai 2003;26(1):31- 32.

Lin JT, Liu WH. o- Orsellinaldehyde from the submerged culture of the edible mushroom Grifola frondosa exhibits selective cytotoxic effect against Hep 3B cells through apoptosis. J Agric Food Chem. 2006 Oct 4;54(20):7564- 9.

Matsui K, Kodama N, Nanba H. Effects of maitake (Grifola frondosa) D- Fraction on the carcinoma angiogenesis. Cancer Lett 10- 30- 2001;172(2):193- 198.

Preuss HG, Echard B, Bagchi D, et al. Enhanced insulin- hypoglycemic activity in rats consuming a specific glycoprotein extracted from maitake mushroom. Mol Cell Biochem 2007 Dec;306(1- 2):105- 13.

Wu MJ, Cheng TL, Cheng SY, et al. Immunomodulatory properties of Grifola frondosa in submerged culture. J Agric Food Chem 2006 Apr 19;54(8):2906- 14.

Yang BK, Gu YA, Jeong YT, et al. Chemical characteristics and immuno- modulating activities of exo- biopolymers produced by Grifola frondosa during submerged fermentation process. Int J Biol Macromol 2007 Aug 1;41(3):227- 33.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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