Generic: Hibiscus esculentis
treats Lice and Hypertension
This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): J. Kathryn Bryan, BS (Natural Standard Research Collaboration); Nicole Giese, MS (Natural Standard Research Collaboration); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).
BibliographyDISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Ali BH, Al Wabel N, Blunden G. Phytochemical, pharmacological and toxicological aspects of Hibiscus sabdariffa L.: a review. Phytother Res 2005;19(5):369- 375.
Brunold C, Deters A, Knoepfel- Sidler F, et al. Polysaccharides from Hibiscus sabdariffa flowers stimulate proliferation and differentiation of human keratinocytes. Planta Med. 2004;70(4):370- 373.
Chang YC, Huang HP, Hsu JD, et al. Hibiscus anthocyanins rich extract- induced apoptotic cell death in human promyelocytic leukemia cells. Toxicol Appl Pharmacol 6- 15- 2005;205(3):201- 212.
Chen JJ, Huang SY, Duh CY, et al. A new cytotoxic amide from the stem wood of Hibiscus tiliaceus. Planta Med 2006;72(10):935- 938.
El Basheir ZM, Fouad MA. A preliminary pilot survey on head lice, pediculosis in Sharkia Governorate and treatment of lice with natural plant extracts. J.Egypt.Soc.Parasitol. 2002;32(3):725- 736.
Frank T, Janssen M, Netzel M, et al. Pharmacokinetics of anthocyanidin- 3- glycosides following consumption of Hibiscus sabdariffa L. extract. J Clin Pharmacol 2005;45(2):203- 210.
Herrera- Arellano A, Flores- Romero S, Chavez- Soto MA, et al. Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension: a controlled and randomized clinical trial. Phytomedicine. 2004;11(5):375- 382.
Hou DX, Tong X, Terahara N, et al. Delphinidin 3- sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species- mediated mitochondrial pathway. Arch Biochem Biophys. 8- 1- 2005;440(1):101- 109.
Kim MS, Kim JK, Kim HJ, et al. Hibiscus extract inhibits the lipid droplet accumulation and adipogenic transcription factors expression of 3T3- L1 preadipocytes. J.Altern.Complement Med. 2003;9(4):499- 504.
Lin HH, Huang HP, Huang CC, et al. Hibiscus polyphenol- rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/ FasL cascade pathway. Mol Carcinog. 2005;43(2):86- 99.
Muthu SE, Nandakumar S, Rao UA. The effect of methanolic extract of Tamarindus indica Linn. on the growth of clinical isolates of Burkholderia pseudomallei. Indian J Med Res 2005;122(6):525- 528.
Tseng TH, Lee YJ. Evaluation of natural and synthetic compounds from East Asiatic folk medicinal plants on the mediation of cancer. Anticancer Agents Med Chem 2006;6(4):347- 365.
Tseng TH, Kao TW, Chu CY, et al. Induction of apoptosis by hibiscus protocatechuic acid in human leukemia cells via reduction of retinoblastoma (RB) phosphorylation and Bcl- 2 expression. Biochem.Pharmacol. 8- 1- 2000;60(3):307- 315.
Varavithya V, Phongkitkarun S, Jatchavala J, et al. The efficacy of roselle (Hibicus sabdariffa Linn.) flower tea as oral negative contrast agent for MRCP study. J Med Assoc Thai 2005;88 Suppl 1:S35- S41.
Wu PL, Wu TS, He CX, et al. Constituents from the stems of Hibiscus taiwanensis. Chem Pharm Bull (Tokyo) 2005;53(1):56- 59.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.