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  • Basic Info
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Generic: Hedera helix
treats Asthma and Chronic obstructive pulmonary disease

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This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration ( J. Kathryn Bryan, BA (Natural Standard Research Collaboration); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Nicole Giese, MS (Natural Standard Research Collaboration); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Amara- Mokrane YA, Lehucher- Michel MP, Balansard G, et al. Protective effects of alpha- hederin, chlorophyllin and ascorbic acid towards the induction of micronuclei by doxorubicin in cultured human lymphocytes. Mutagenesis 1996;11(2):161- 167.

Billington T, Pharmawati M, Gehring CA. Isolation and immunoaffinity purification of biologically active plant natriuretic peptide. Biochem Biophys Res Commun. 6- 27- 1997;235(3):722- 725.

Gaillard Y, Blaise P, Darre A, et al. An unusual case of death: suffocation caused by leaves of common ivy (Hedera helix). Detection of hederacoside C, alpha- hederin, and hederagenin by LC- EI/ MS- MS. J Anal Toxicol 2003;27(4):257- 262.

Garcia M, Fernandez E, Navarro JA, et al. Allergic contact dermatitis from Hedera helix L. Contact Dermatitis 1995;33(2):133- 134.

Gulcin I, Mshvildadze V, Gepdiremen A, et al. Antioxidant activity of saponins isolated from ivy: alpha- hederin, hederasaponin- C, hederacolchiside- E and hederacolchiside- F. Planta Med 2004;70(6):561- 563.

Guo R, Pittler MH, Ernst E. Herbal medicines for the treatment of COPD: a systematic review. Eur Respir.J 2006;28(2):330- 338.

Hofmann D, Hecker M, Volp A. Efficacy of dry extract of ivy leaves in children with bronchial asthma- - a review of randomized controlled trials. Phytomedicine 2003;10(2- 3):213- 220.

Johnke H, Bjarnason B. [Contact dermatitis allergy to common ivy (Hedera helix L.)]. Ugeskr Laeger 6- 20- 1994;156(25):3778- 3779.

Jors E. [The prevalence of skin and mucosal symptoms in gardeners handling Ficus benjamina (weeping fig) and Hedera helix (ivy). A cross- sectional study]. Ugeskr.Laeger 9- 8- 2003;165(37):3526- 3529.

Massmanian A, Valcuende Cavero F, Ramirez Bosca A, et al. Contact dermatitis from variegated ivy (Hedera helix subsp. canariensis Willd.). Contact Dermatitis 1988;18(4):247- 248.

Oka K, Saito F, Yasuhara T, et al. The allergens of Dendropanax trifidus Makino and Fatsia japonica Decne. et Planch. and evaluation of cross- reactions with other plants of the Araliaceae family. Contact Dermatitis 1999;40(4):209- 213.

Ozdemir C, Schneider LA, Hinrichs R, et al. [Allergic contact dermatitis to common ivy (Hedera helix L.)]. Hautarzt 2003;54(10):966- 969.

Taylor P. Healthy household hints. STEP Perspect 1999;99(3):16.

Villani P, Orsiere T, Sari- Minodier I, et al. [In vitro study of the antimutagenic activity of alphahederin]. Ann Biol Clin (Paris) 2001;59(3):285- 289.

Yesudian PD, Franks A. Contact dermatitis from Hedera helix in a husband and wife. Contact Dermatitis 2002;46(2):125- 126.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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