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  • Basic Info
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Generic: Guggul
treats Obesity, Rheumatoid arthritis, Osteoarthritis, Acne, and Hypercholesterolemia
               



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Attribution

This information is based on a professional level monograph edited and peer- reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Serguei Axentsev MD, PhD, Dr.Sci (Natural Standard Research Collaboration); Ethan Basch, MD (Memorial Sloan- Kettering Cancer Center); Heather Boon B.Sc.Phm, PhD (University of Toronto); Levi Garraway, MD, PhD (Harvard Medical School); Paul Hammerness, MD (Harvard Medical School); David Kroll, PhD (Duke University); Philippe Szapary, MD (University of Pennsylvania); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Mamta Vora, PharmD (Northeastern University); Wendy Weissner, BA (Natural Standard Research Collaboration).

Bibliography

DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Agarwal RC, Singh SP, Saran RK, et al. Clinical trial of gugulipid- - a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626- 634.

Antonio J, Colker CM, Torina GC, et al. Effects of a standardized guggulsterone phosphate supplement on body composition in overweight adults: A pilot study. Curr Ther Res 1999;60:220- 227.

Dalvi SS, Nayak VK, Pohujani SM, et al. Effect of gugulipid on bioavailability of diltiazem and propranolol. J Assoc Physicians India 1994;42(6):454- 455.

Dogra J, Aneja N, Saxena VN. Oral gugulipid in acne vulgaris management. Ind J Dermatol Venereol Leprol 1990;56(1):381- 383.

Gaur SP, Garg RK, Kar AM, et al. Gugulipid, a new hypolipidaemic agent, in patients of acute ischaemic stroke: effect on clinical outcome, platelet function and serum lipids. Asia Pacif J Pharm 1997;12:65- 69.

Ghorai M, Mandal SC, Pal M, et al. A comparative study on hypocholesterolaemic effect of allicin, whole germinated seeds of bengal gram and guggulipid of gum gugglu. Phytother Res 2000;14(3):200- 202.

Kesava RG, Dhar SC. Effect of a new non- steroidal anti- inflammatory agent on lysosomal stability in adjuvant induced arthritis. Ital J Biochem 1987;36(4):205- 217.

Kotiyal JP, Singh DS, Bisht DB. Gum guggulu (Commiphora mukul) fraction 'A' in obesity - - a double- blind clinical trial. J Res Ayur and Siddha 1985;6(1,3,4):20- 35.

Malhotra SC, Ahuja MM, Sundaram KR. Long term clinical studies on the hypolipidaemic effect of Commiphora mukul (Guggulu) and clofibrate. Indian J Med Res 1977;65(3):390- 395.

Mester L, Mester M, Nityanand S. Inhibition of platelet aggregation by "guggulu" steroids. Planta Med 1979;37(4):367- 369.

Nies LK, Cymbala AA, Kasten SL, et al. Complementary and alternative therapies for the management of dyslipidemia. Ann Pharmacother. 2006 Nov;40(11):1984- 92.

Nityanand S, Srivastava JS, Asthana OP. Clinical trials with gugulipid. A new hypolipidaemic agent. J Assoc Physicians India 1989;37(5):323- 328.

Singh BB, Mishra L, Aquilina N, et al. Usefulness of guggul (Commiphora mukul) for osteoarthritis of the knee: An experimental case study. Altern Ther Health Med 2001;7(2):120, 112- 114.

Szapary PO, Wolfe ML, Bloedon LT, et al. Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial. JAMA 2003;290(6):765- 772.

Ulbricht C, Basch E, Szapary P, et al. Guggul for hyperlipidemia: a review by the Natural Standard Research Collaboration. Complement Ther Med. 2005 Dec;13(4):279- 90.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

               
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