treats Laxative/bowel preparation for procedures, Burns, Exercise performance, Hypercalcemia, Bone density, Total parenteral nutrition, Refeeding syndrome prevention, Vitamin D resistant rickets, Kidney stones, Diabetic ketoacidosis, Hyperparathyroidism, Constipation, Hypercalciuria, and Hypophosphatemia
Alternate TitleFleet Phospho- soda, Fleet Enema
CategoryHerbs & Supplements
Aluminum phosphate, calcium phosphate (bone ash, bone phosphate, calcium orthophosphate, calcium phosphate dibasic anhydrous, calcium phosphate dibasic dihydrate, calcium phosphate tribasic, di- calcium phosphate, dicalcium phosphate, dicalcium phosphates, neutral calcium phosphate, precipitated calcium phosphate, tertiary calcium phosphate, tricalcium phosphate, whitlockite), potassium phosphate (dibasic potassium phosphate, dipotassium hydrogen orthophosphate, dipotassium monophosphate, dipotassium phosphate, monobasic potassium phosphate, potassium acid phosphate, potassium biphosphate, potassium dihydrogen orthophosphate), MCI- 196 (colestilan), sevelamar (Renagel®), sodium phosphate (anhydrous sodium phosphate, dibasic sodium phosphate, disodium hydrogen orthophosphate, disodium hydrogen orthophosphate dodecahydrate, disodium hydrogen phosphate, disodium phosphate, phosphate of soda, sodium orthophosphate).
Note on terminology: The term "phosphates" in this monograph refers to anhydrous sodium acid phosphate, dibasic sodium phosphate, dipotassium phosphate anhydrous, monobasic potassium acid phosphate, monobasic sodium phosphate, phosphorus, potassium phosphate, sodium biphosphate, and sodium phosphate.
Caution: Do not confuse phosphate salts with toxic substances such as organophosphates, or with tribasic sodium phosphates and tribasic potassium phosphates, which are strongly alkaline.
Phosphorus is a mineral found in many foods, such as milk, cheese, dried beans, peas, colas, nuts, and peanut butter. Phosphate is the most common form of phosphorus. In the body, phosphate is the most abundant intracellular anion. It is critical for energy storage and metabolism, for the utilization of many B- complex vitamins, to buffer body fluids, for kidney excretion of hydrogen ions, for proper muscle and nerve function, and for maintaining calcium balance. Phosphorus is vital to the formation of bones and teeth, and healthy bones and soft tissues require calcium and phosphorus to grow and develop throughout life. Inadequate intake of dietary phosphate can lead to hypophosphatemia (low levels of phosphate in the blood), which can lead to long- term potentially serious complications. Conversely, excess phosphate intake can lead to hyperphosphatemia (high blood phosphorus levels), which can occur particularly in people with impaired kidney function and can lead to potentially serious electrolyte imbalances, adverse effects, or death.
In adults, phosphorus makes up approximately 1% of total body weight It is present in every cell of the body, although 85% of the body's phosphorus is found in the bones and teeth.
Phosphates are used clinically to treat hypophosphatemia, hypercalcemia (high blood calcium levels), as saline laxatives, and in the management of calcium- based kidney stones. They may also be of some benefit to patients with vitamin D resistant rickets, multiple sclerosis, and diabetic ketoacidosis.