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  • Basic Info
Licensed from
Generic: Cytisus
treats Labor induction, Diuretic, and Cardiovascular conditions
               



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Interactions

Interactions with Drugs

Scotch broom contains the alkaloid sparteine, which may affect cardiac conductivity. Use in individuals taking other heart medications that affect heart rhythm such as digoxin, beta- blockers, calcium channel blockers, or other antiarrhythmics may be hazardous and should be avoided unless under strict medical supervision.

Scotch broom contains the alkaloid sparteine, which can potentially increase (or decrease) blood pressure. Use is not recommended in patients with a history of abnormal blood pressure or taking blood pressure medications.

Scotch broom contains the toxic alkaloid sparteine, which is metabolized (broken down) by the liver's cytochrome P450 2D6 (CYP2D6) isoenzyme system. Therefore, drugs that inhibit CYP2D6 can increase the potential toxicity of scotch broom, including a risk of life- threatening adverse events such as cardiovascular collapse. This includes the drugs amiodarone, celecoxib, chlorpheniramine, cimetidine, clomipramine, cocaine, doxorubicin, halofantrine, haloperidol, methadone, mibefradil, meclobemide, nefazodone, quinidine, ranitidine, ritonavir, terbinafine, venlafaxine, and multiple antidepressants in the selective serotonin reuptake inhibitor (SSRI) class, particularly fluoxetine and paroxetine. In particular, the drug haloperidol (Haldol®) has been shown to increase blood levels of sparteine.

Scotch broom contains small amounts of tyramine, which can lead to hypertensive crisis in individuals taking MAOI drugs. Therefore, this combination should be avoided. MAOI drugs include Isocarboxazid (Marplan®), phenelzine (Nardil®), and tranylcypromine (Parnate®).

Interactions with Herbs and Dietary Supplements

Scotch broom contains the alkaloid sparteine, which can potentially decrease or increase blood pressure. Use is not recommended in patients with a history of abnormal blood pressure or taking agents with significant effects on blood pressure.

Herbs with potential effects on heart rhythm similar to digoxin may pose a risk of heart block or abnormal cardiac rhythms when used with scotch broom, which contains the cardioactive constituent sparteine.

Scotch broom contains the toxic alkaloid sparteine, which is metabolized (broken down) by the liver's cytochrome P450 2D6 (CYP2D6) isoenzyme system. Therefore, herbs that inhibit CYP2D6 can increase the potential toxicity of scotch broom, including a risk of life- threatening adverse events such as cardiovascular collapse.

Scotch broom contains small amounts of tyramine, which can lead to hypertensive crisis in individuals taking MAOI agents. Therefore, this combination should be avoided.

               
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